Novel glucocorticold receptor agonists

Abstract

This invention relates to novel glucocorticoid receptor agonists of formula (I): and to processes and intermediates for their preparation. The present invention also relates to pharmaceutical compositions containing these compounds, to their combination with one or more other therapeutic agents, as well as to their use for the treatment of a number of inflammatory and allergic diseases, disorders and conditions.

1 . A compound of formula (I): 
       
         
           
           
               
               
           
         
       
       wherein R 1  is 
       
         
           
           
               
               
           
         
         wherein * represent the attachment point of R 1  to the carbon of the phenyl cycle; 
         or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate of said compound or salt. 
       
     
     
         2 - 4 . (canceled) 
     
     
         5 . A pharmaceutical composition comprising an effective amount of a compound of the formula (I) as described in  claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 
     
     
         6 - 18 . (canceled)