US2009171071A1PendingUtilityA1

PYY Agonists and Uses Thereof

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Assignee: PFIZERPriority: Feb 4, 2005Filed: Feb 26, 2009Published: Jul 2, 2009
Est. expiryFeb 4, 2025(expired)· nominal 20-yr term from priority
Inventors:Neena SummersRory R. FinnNed R. SiegelNancy A. Nardone
A61P 5/48A61P 43/00A61P 3/04A61P 3/00A61K 38/00A61K 47/60C07K 14/575C07K 14/00A61K 38/16
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Claims

Abstract

The invention provides PYY 3-36 variants and pegylated derivatives thereof and compositions and methods useful in the treatment of conditions modulated by an NPY Y2 receptor agonist.

Claims

exact text as granted — not AI-modified
1 - 37 . (canceled) 
     
     
         38 . A polynucleotide encoding the polypeptide of SEQ ID NO:3 or SEQ ID NO:4. 
     
     
         39 . A monoclonal antibody that specifically binds to a polypeptide comprising the amino acid sequence as shown in SEQ ID NO:3 or SEQ ID NO:4. 
     
     
         40 . The monoclonal antibody of  claim 39 , wherein said polypeptide is pegylated at the cysteine residue.

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