Novel polypeptide

Abstract

Polynucleotide and polypeptide sequences are described. The polypeptide sequences comprise one or more of: (a) a polypeptide having the deduced amino acid sequence translated from the polynucleotide sequence in SEQ ID NO: 1 and variants, fragments, homologues, analogues and derivatives thereof; (b) a polypeptide of SEQ ID NO: 2 and variants, fragments, homologues, analogues and derivatives thereof; or (c) a polypeptide encoded by the cDNA of NCIMB 41066 and variants, fragments, homologues, analogues and derivatives thereof.

1 - 12 . (Cancelled).  
     
     
         13 . A polypeptide comprising: 
 (a) an amino acid sequence encoded by a polynucleotide sequence of SEQ ID NO: 1;    (b) the amino acid sequence of SEQ ID NO: 2;    (c) an amino acid sequence encoded by the cDNA contained in the clone deposited as National Collections of Industrial and Marine Bacteria Limited (NCIMB) 41066; or    (d) an amino acid sequence encoded by a polynucleotide that has at least 95% identity to the nucleotide sequence of SEQ ID NO: 1 and encodes a neuromedin U receptor that mediates, in HEK-293 cells transfected with and expressing said polynucleotide, a specific neuromedin U-induced increase in intracellular calcium following contact with neuromedin U.    
     
     
         14 . An antibody against the polypeptide of  claim 13 .  
     
     
         15 . (Cancelled).  
     
     
         16 . A pharmaceutical composition comprising the antibody of  claim 14  and one or more pharmaceutically acceptable carriers, diluents, adjuvants or excipients.  
     
     
         17 - 22 . (Cancelled).