Inventor · disambiguated record
Kirston E. Koths
Also filed as: KOTHS KIRSTON · KOTHS KIRSTON E
45 granted patents·5 pending applications·1,765 citations·filing 1984–2018
99Inventor score
Files withCHIRON CORP25CETUS CORP12CETUS ONCOLOGY CORP4NOVARTIS VACCINES & DIAGNOSTICS INC4KAVANAUGH WILLIAM M2
Top patents by PatentIndex Score
50 records- 0198US4847325AConjugation of polymer to colony stimulating factor-1CETUS CORP·Filed 1988·Granted Jul 11, 1989·403 cites·26 claims
- 0295US5153265AConjugation of polymer to colony stimulating factor-1CETUS CORP·Filed 1989·Granted Oct 6, 1992·179 cites·33 claims
- 0395US5116943AOxidation-resistant muteins of Il-2 and other proteinCETUS CORP·Filed 1988·Granted May 26, 1992·230 cites·13 claims
- 0495US4572798AMethod for promoting disulfide bond formation in recombinant proteinsCETUS CORP·Filed 1984·Granted Feb 25, 1986·119 cites·19 claims
- 0595US4569790AProcess for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositionsCETUS CORP·Filed 1984·Granted Feb 11, 1986·81 cites·21 claims
- 0691US4752585AOxidation-resistant muteinsCETUS CORP·Filed 1986·Granted Jun 21, 1988·91 cites·12 claims
- 0789US9926371B2M-CSF specific monoclonal antibody and uses thereofNOVARTIS VACCINES & DIAGNOSTICS INC·Filed 2016·Granted Mar 27, 2018·7 cites·17 claims
- 0889US9079956B2M-CSF specific monoclonal antibody and uses thereofNOVARTIS VACCINES & DIAGNOSTIC·Filed 2014·Granted Jul 14, 2015·11 cites·30 claims
- 0987US6184354B1Soluble extracellular domain of human M-CSF receptorCHIRON CORP·Filed 1995·Granted Feb 6, 2001·50 cites·3 claims
- 1085US5104975ACompositions for detecting ras gene proteins and cancer therapeuticsCETUS CORP·Filed 1988·Granted Apr 14, 1992·48 cites·18 claims
- 1185US4894227AComposition of immunotoxins with interleukin-2CETUS CORP·Filed 1987·Granted Jan 16, 1990·58 cites·10 claims
- 1283US4863726ACombination therapy using immunotoxins with interleukin-2CETUS CORP·Filed 1987·Granted Sep 5, 1989·52 cites·12 claims
- 1381US5866114ACrystallization of M-CSFαCHIRON CORP·Filed 1993·Granted Feb 2, 1999·52 cites·42 claims
- 1479US5234839ACompositions for detecting ras gene proteins and cancer therapeuticsCETUS ONCOLOGY CORP·Filed 1991·Granted Aug 10, 1993·47 cites·8 claims
- 1578USRE35171ECompositions for detecting ras gene proteins and cancer therapeuticsCETUS ONCOLOGY CORP·Filed 1994·Granted Mar 5, 1996·36 cites·18 claims
- 1676US5573930ADNA encoding various forms of colony stimulating factor-1CETUS ONCOLOGY CORP·Filed 1992·Granted Nov 12, 1996·31 cites·17 claims
- 1772US9522186B2M-CSF specific monoclonal antibody and uses therofNOVARTIS VACCINES & DIAGNOSTICS INC·Filed 2015·Granted Dec 20, 2016·1 cites·22 claims
- 1872US5491065AMonoclonal antibodies that bind to and neutralize dimeric but not monomeric human M-CSF and methods of use thereof for detection of dimeric M-CSFCETUS ONCOLOGY CORP·Filed 1993·Granted Feb 13, 1996·36 cites·10 claims
- 1970US5614185ACompositions containing reduced, microbially produced interleukin-2 (IL-2)CHIRON CORP·Filed 1995·Granted Mar 25, 1997·24 cites·10 claims
- 2069US11034759B2Humanized M-CSF specific monoclonal antibodies, kits, and uses thereofNOVARTIS VACCINES & DIAGNOSTICS INC·Filed 2018·Granted Jun 15, 2021·0 cites·27 claims
- 2166US5965382ANucleic acid encoding secreted Mac-2 binding glycoproteinCHIRON CORP·Filed 1994·Granted Oct 12, 1999·13 cites·22 claims
- 2265US5998378ACompositions for the inhibition of TNF hormone formation and uses thereofCHIRON CORP·Filed 1994·Granted Dec 7, 1999·28 cites·14 claims
- 2364US6204020B1DNA encoding N∇2 CSF-1 (short form) and carboxy truncated fragment thereofCHIRON CORP·Filed 1995·Granted Mar 20, 2001·12 cites·10 claims
- 2464US5643563AN-∇3 deletion mutants of the short form of CSF-1CHIRON CORP·Filed 1995·Granted Jul 1, 1997·12 cites·14 claims
- 2563US5681719ADNA encoding N- and C- terminally truncated colony stimulating factor-1 variantsCHIRON CORP·Filed 1995·Granted Oct 28, 1997·11 cites·27 claims
- 2662US5419899APurified, reduced recombinant interleukin-2 compositionsFiled 1992·Granted May 30, 1995·13 cites·24 claims
- 2761US2018171009A1M-CSF Specific Monoclonal Antibody and Uses ThereofNOVARTIS VACCINES & DIAGNOSTICS INC·Filed 2018·Application pending·0 cites
- 2859US6322779B1Recombinant human CSF-1 dimer and compositions thereofCHIRON CORP·Filed 1995·Granted Nov 27, 2001·18 cites·14 claims
- 2958US6146851ADNA encoding NV2 (long form) and carboxy truncated fragments thereofCHIRON CORP·Filed 1995·Granted Nov 14, 2000·10 cites·10 claims
- 3057US6117422AN∇2-CSF-1(long form) and carboxy truncated fragments thereofCHIRON CORP·Filed 1995·Granted Sep 12, 2000·14 cites·18 claims
- 3157US6069127ASecreted mac-2-binding glycoproteinCHIRON CORP·Filed 1995·Granted May 30, 2000·9 cites·7 claims
- 3257US5644035AMethod for purifying secreted Mac-2-binding glycoproteinCHIRON CORP·Filed 1995·Granted Jul 1, 1997·10 cites·2 claims
- 3356US2009324604A1M-csf specific monoclonal antibody and uses thereofCHIRON CORP·Filed 2005·Application pending·0 cites
- 3453US6103224AN∇2 CSF-1 (short form) and carboxy truncated fragments thereofCHIRON CORP·Filed 1995·Granted Aug 15, 2000·11 cites·11 claims
- 3553US4569913AP. obtusus pyranose-2-oxidase preparationCETUS CORP·Filed 1984·Granted Feb 11, 1986·9 cites·6 claims
- 3652US2014093492A1Method for preventing and treating cancer metastasis and bone loss associated with cancer metastasisZIMMERMAN DEBORAH LEE·Filed 2013·Application pending·0 cites
- 3749US2011091451A1Methods for preventing and treating cancer metastasis and bone loss associated with cancer metastasisKAVANAUGH WILLIAM M·Filed 2004·Application pending·0 cites
- 3845US2012045450A1Method for preventing and treating cancer metastasis and bone loss associated with cancer metastasisKAVANAUGH WILLIAM M·Filed 2011·Application pending·0 cites
- 3944US6025146AIdentification of M-CSF agonists and antagonistsCHIRON CORP·Filed 1995·Granted Feb 15, 2000·13 cites·8 claims
- 4043US5861150ARecombinant human CSF-1 dimer and compositions thereofCHIRON CORP·Filed 1995·Granted Jan 19, 1999·5 cites·20 claims
- 4143US5651963AHeterodimers forms of CSF-1 and pharmaceutical compositions thereofCHIRON CORP·Filed 1994·Granted Jul 29, 1997·4 cites·10 claims
- 4243US4569910AMethods and reagents for pyranosone productionCETUS CORP·Filed 1984·Granted Feb 11, 1986·4 cites·45 claims
- 4337US5672343AN- 3 deletion mutants of the long form of CSF-1CHIRON CORP·Filed 1995·Granted Sep 30, 1997·1 cites·15 claims
- 4435US6599706B1Recombinant PR-3 and assays employing the sameCHIRON CORP·Filed 1995·Granted Jul 29, 2003·3 cites·6 claims
- 4535US5843693AAssay method for screening for inhibitors of proTNF conversionCHIRON CORP·Filed 1995·Granted Dec 1, 1998·3 cites·2 claims
- 4634US4568645AFungal pyranose-2-oxidase preparationsCETUS CORP·Filed 1984·Granted Feb 4, 1986·3 cites·6 claims
- 4732US6586222B1Recombinant PR-3 and compositions thereofCHIRON CORP·Filed 1995·Granted Jul 1, 2003·1 cites·29 claims
- 4832US5736340ASecreted Mac-2-binding glycoproteinCHIRON CORP·Filed 1995·Granted Apr 7, 1998·0 cites·2 claims
- 4930US5830684ANative type II GAP, methods for purifying various GAPs and uses of GAPs to diagnose cancerCHIRON CORP·Filed 1990·Granted Nov 3, 1998·2 cites·7 claims
- 5029US6156300APoint mutants of N∇2 CSF-1 and carboxy truncated fragments thereofCHIRON CORP·Filed 1995·Granted Dec 5, 2000·0 cites·43 claims
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