Assignee
CHIRON CORP
US·654 granted patents·130 pending applications·44,724 citations·filing 1982–2010
Top patents by PatentIndex Score
784 records- 0199US5635352ASolution phase nucleic acid sandwich assays having reduced background noiseCHIRON CORP·Filed 1995·Granted Jun 3, 1997·586 cites·25 claims
- 0299US5597909APolynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and useCHIRON CORP·Filed 1994·Granted Jan 28, 1997·1.3k cites·26 claims
- 0399US5591584AN-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewithCHIRON CORP·Filed 1995·Granted Jan 7, 1997·963 cites·23 claims
- 0499US5580731AN-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewithCHIRON CORP·Filed 1994·Granted Dec 3, 1996·968 cites·27 claims
- 0599US5578717ANucleotides for introducing selectably cleavable and/or abasic sites into oligonucleotidesCHIRON CORP·Filed 1995·Granted Nov 26, 1996·792 cites·11 claims
- 0699US5552538AOligonucleotides with cleavable sitesCHIRON CORP·Filed 1995·Granted Sep 3, 1996·816 cites·1 claims
- 0799US5545730AMultifunctional nucleic acid monomerCHIRON CORP·Filed 1995·Granted Aug 13, 1996·921 cites·1 claims
- 0899US5367066AOligonucleotides with selectably cleavable and/or abasic sitesCHIRON CORP·Filed 1991·Granted Nov 22, 1994·1.3k cites·23 claims
- 0999US5118605APolynucleotide determination with selectable cleavage sitesCHIRON CORP·Filed 1988·Granted Jun 2, 1992·460 cites·12 claims
- 1099US5093232ANucleic acid probesCHIRON CORP·Filed 1986·Granted Mar 3, 1992·277 cites·14 claims
- 1199US4517338AMultiple reactor system and method for polynucleotide synthesisCHIRON CORP·Filed 1984·Granted May 14, 1985·221 cites·19 claims
- 1298US6525102B1Stabilized liquid polypeptide-containing pharmaceutical compositionsCHIRON CORP·Filed 2000·Granted Feb 25, 2003·148 cites·58 claims
- 1398US6312923B1Method for expression of heterologous proteins in yeastCHIRON CORP·Filed 2000·Granted Nov 6, 2001·102 cites·11 claims
- 1498US6054561AAntigen-binding sites of antibody molecules specific for cancer antigensCHIRON CORP·Filed 1995·Granted Apr 25, 2000·362 cites·31 claims
- 1598US5877305ADNA encoding biosynthetic binding protein for cancer markerCHIRON CORP·Filed 1994·Granted Mar 2, 1999·285 cites·3 claims
- 1698US5843723AAlphavirus vector constructsCHIRON CORP·Filed 1996·Granted Dec 1, 1998·327 cites·47 claims
- 1798US5789245AAlphavirus structural protein expression cassettesCHIRON CORP·Filed 1996·Granted Aug 4, 1998·345 cites·29 claims
- 1898US5681697ASolution phase nucleic acid sandwich assays having reduced background noise and kits thereforCHIRON CORP·Filed 1993·Granted Oct 28, 1997·297 cites·8 claims
- 1998US5677165AAnti-CD40 monoclonal antibodies capable of blocking B-cell activationCHIRON CORP·Filed 1993·Granted Oct 14, 1997·212 cites·11 claims
- 2098US5534254ABiosynthetic binding proteins for immuno-targetingCHIRON CORP·Filed 1993·Granted Jul 9, 1996·288 cites·30 claims
- 2198US5258506APhotolabile reagents for incorporation into oligonucleotide chainsCHIRON CORP·Filed 1989·Granted Nov 2, 1993·950 cites·9 claims
- 2298US5124246ANucleic acid multimers and amplified nucleic acid hybridization assays using sameCHIRON CORP·Filed 1989·Granted Jun 23, 1992·1.3k cites·59 claims
- 2398US4775619APolynucleotide determination with selectable cleavage sitesCHIRON CORP·Filed 1984·Granted Oct 4, 1988·316 cites·25 claims
- 2498US4751180AExpression using fused genes providing for protein productCHIRON CORP·Filed 1986·Granted Jun 14, 1988·800 cites·22 claims
- 2598US4722840AHybrid particle immunogensCHIRON CORP·Filed 1985·Granted Feb 2, 1988·203 cites·13 claims
- 2698US4510245AAdenovirus promoter systemCHIRON CORP·Filed 1982·Granted Apr 9, 1985·656 cites·6 claims
- 2797US6716626B1Human FGF-21 nucleic acidsCHIRON CORP·Filed 2000·Granted Apr 6, 2004·226 cites·8 claims
- 2897US6677445B1Chimeric antisense oligonucleotides and cell transfecting formulations thereofCHIRON CORP·Filed 2000·Granted Jan 13, 2004·75 cites·7 claims
- 2997US6605617B2Quinolinone derivativesCHIRON CORP·Filed 2001·Granted Aug 12, 2003·174 cites·30 claims
- 3097US6534064B1Stabilized protein particles for inducing cellular immune responsesCHIRON CORP·Filed 2000·Granted Mar 18, 2003·75 cites·49 claims
- 3197US6313093B1Method for administering insulin to the brainCHIRON CORP·Filed 1999·Granted Nov 6, 2001·160 cites·30 claims
- 3297US6299884B1Adjuvant formulation comprising a submicron oil droplet emulsionCHIRON CORP·Filed 1995·Granted Oct 9, 2001·255 cites·14 claims
- 3397US5849481ANucleic acid hybridization assays employing large comb-type branched polynucleotidesCHIRON CORP·Filed 1995·Granted Dec 15, 1998·417 cites·6 claims
- 3497US5681702AReduction of nonspecific hybridization by using novel base-pairing schemesCHIRON CORP·Filed 1994·Granted Oct 28, 1997·429 cites·8 claims
- 3597US5430136AOligonucleotides having selectably cleavable and/or abasic sitesCHIRON CORP·Filed 1990·Granted Jul 4, 1995·108 cites·8 claims
- 3697US5401465ALuminometer with reduced sample crosstalkCHIRON CORP·Filed 1992·Granted Mar 28, 1995·276 cites·8 claims
- 3797US4876197AEukaryotic regulatable transcriptionCHIRON CORP·Filed 1985·Granted Oct 24, 1989·248 cites·14 claims
- 3897US4870008ASecretory expression in eukaryotesCHIRON CORP·Filed 1987·Granted Sep 26, 1989·273 cites·37 claims
- 3996US7198899B2Use of NRG4, or inhibitors thereof, in the treatment of colon and pancreatic cancersCHIRON CORP·Filed 2003·Granted Apr 3, 2007·142 cites·3 claims
- 4096US6991785B2Method for administering a cytokine to the central nervous system and the lymphatic systemCHIRON CORP·Filed 2002·Granted Jan 31, 2006·87 cites·48 claims
- 4196US6861410B1Immunological adjuvant compositionsCHIRON CORP·Filed 2002·Granted Mar 1, 2005·60 cites·24 claims
- 4296US6767699B2Method for the quantitation of alphavirus replicon particlesCHIRON CORP·Filed 2001·Granted Jul 27, 2004·50 cites·5 claims
- 4396US6451325B1Adjuvant formulation comprising a submicron oil droplet emulsionCHIRON CORP·Filed 1995·Granted Sep 17, 2002·174 cites·49 claims
- 4496US6376236B1Recombinant alphavirus particlesCHIRON CORP·Filed 1999·Granted Apr 23, 2002·121 cites·11 claims
- 4596US6329201B1Compositions and methods for packaging of alphavirus vectorsCHIRON CORP·Filed 2000·Granted Dec 11, 2001·86 cites·10 claims
- 4696US6180603B1Method for administering neurologic agents to the brainCHIRON CORP·Filed 1997·Granted Jan 30, 2001·131 cites·41 claims
- 4796US6086901AUse of microparticles combined with submicron oil-in-water emulsionsCHIRON CORP·Filed 1998·Granted Jul 11, 2000·119 cites·14 claims
- 4896US6015694AMethod for stimulating an immune response utilizing recombinant alphavirus particlesCHIRON CORP·Filed 1997·Granted Jan 18, 2000·228 cites·11 claims
- 4996US5874082AHumanized anti-CD40 monoclonal antibodies and fragments capable of blocking B cell proliferationCHIRON CORP·Filed 1996·Granted Feb 23, 1999·175 cites·20 claims
- 5096USRE35749EConstructs of glyceraldehyde-3-phosphate dehydrogenase promoter and methods for expressing genes using said constructsCHIRON CORP·Filed 1996·Granted Mar 17, 1998·143 cites·4 claims
Showing the top 50 of 784 patent records by PatentIndex Score.
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