Compositions comprising Lactobacillus plantarum strains in combination with tannin and new Lactobacillus plantarum strains

Abstract

The invention refers to a composition comprising one or more tannase-producing strains of Lactobacillus having the ability to adhere to the human intestinal mucosa in combination with tannin. New tannase-producing strains of Lactobacillus plantarum are a.

The invention claimed is: 
     
       1. A composition comprising:
 (a) one or more isolated tannase-producing strains of Lactobacillus plantarum; and 
 (b) tannin; 
 wherein said one or more isolated tannase-producing strains of Lactobacillus plantarum are selected from the group consisting of: Lactobacillus plantarum strain HEAL 9, which is deposited as DSM 15312; Lactobacillus plantarum strain HEAL 19, which is deposited as DSM 15313; Lactobacillus plantarum strain HEAL 99, which is deposited as DSM 15316; and combinations thereof. 
 
     
     
       2. The composition according to  claim 1 , wherein said composition further comprises a carrier. 
     
     
       3. The composition according to  claim 1  which is a food composition. 
     
     
       4. The composition according to  claim 1  which is a pharmaceutical composition. 
     
     
       5. A isolated tannase-producing strain of Lactobacillus plantarum, wherein said isolated tannase-producing strain of Lactobacillus plantarum is selected from the group consisting of: Lactobacillus plantarum strain HEAL 9, which is deposited as DSM 15312; Lactobacilus plantarum strain HEAL 19, which is deposited as DSM 15313; and Lactobacillus plantarum strain HEAL 99, which is deposited as DSM 15316. 
     
     
       6. The isolated tannase-producing strain according to  claim 5 , wherein said isolated tannase-producing strain is Lactobacillus plantarum strain HEAL 9, which is deposited as DSM 15312. 
     
     
       7. The isolated tannase-producing strain according to  claim 5 , wherein said isolated tannase-producing strain is Lactobacillus plantarum strain HEAL 19, which is deposited as DSM 15313. 
     
     
       8. The isolated tannase-producing strain according to  claim 5 , wherein said isolated tannase-producing strain is Lactobacillus plantarum strain HEAL 99, which is deposited as DSM 15316. 
     
     
       9. A medicament for prophylactic or curative treatment of cardiovascular diseases, diabetes, inflammatory bowel diseases (IBD), irritable bowel syndrome (IBS), gastrointestinal infections, cancer, Alzheimer's disease or diseases with an autoimmune origin, wherein said medicament comprises:
 (a) one or more isolated tannase-producing strains of Lactobacillus plantarum having the ability to adhere to the human intestinal mucosa; and 
 (b) tannin; 
 wherein said one or more isolated tannase-producing strains of Lactobacillus plantarum are selected from the group consisting of: Lactobacillus plantarum strain HEAL 9, which is deposited as DSM 15312; Lactobacillus plantarum strain HEAL 19, which is deposited as DSM 15313; Lactobacillus plantarum strain HEAL 99, which is deposited as DSM 15316; and combinations thereof. 
 
     
     
       10. A composition for the preservation of food comprising:
 (a) one or more isolated tannase-producing strains of Lactobacillus plantarum having the ability to adhere to the human intestinal mucosa; and 
 (b) tannin; 
 wherein said one or more isolated tannase-producing strains of Lactobacillus plantarum are selected from the group consisting of: Lactobacillus plantarum strain HEAL 9, which is deposited as DSM 15312; Lactobacillus plantarum strain HEAL 19, which is deposited as DSM 15313; Lactobacillus plantarum strain HEAL 99, which is deposited as DSM 15316; and combinations thereof. 
 
     
     
       11. A food product comprising:
 (a) one or more isolated tannase-producing strains of Lactobacillus plantarum having the ability to adhere to the human intestinal mucosa; and 
 (b) tannin; 
 wherein said one or more isolated tannase-producing strains of Lactobacillus plantarum are selected from the group consisting of: Lactobacillus plantarum strain HEAL 9, which is deposited as DSM 15312; Lactobacillus plantarum strain HEAL 19, which is deposited as DSM 15313; Lactobacillus plantarum strain HEAL 99, which is deposited as DSM 15316; and combinations thereof. 
 
     
     
       12. The composition according to  claim 2  which is a food composition. 
     
     
       13. The composition according to  claim 2  which is a pharmaceutical composition. 
     
     
       14. A method for prophylactic or curative treatment of inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), or gastrointestinal infection comprising administering to an individual with an inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), or a gastrointestinal infection, in combination with a tannin, a tannase-producing strain of Lactobacillus plantarum having the ability to adhere to the human intestinal mucosa, wherein the tannase-producing strain of Lactobacillus plantarum is selected from the group consisting of Lactobacillus plantarum HEAL 9, which is deposited as DSM 15312; Lactobacillus plantarum HEAL 19, which is deposited as DSM 15313; Lactobacillus plantarum HEAL 99, which is deposited as DSM 15316; and combinations thereof.