USRE43309EExpiredUtility

Immunoregulatory compositions

Assignee: KHAN NISAR AHMEDPriority: Mar 29, 2000Filed: Mar 17, 2011Granted: Apr 10, 2012
Est. expiryMar 29, 2020(expired)· nominal 20-yr term from priority
C07K 5/1021C07K 5/1024A61K 38/06C07K 7/08C07K 5/1013C07K 5/081C07K 5/0806A61P 43/00C07K 4/00C07K 5/06008A61K 38/10A61K 38/00A61K 38/07C07K 5/101C07K 14/59C07K 5/1008C07K 7/06C07K 5/0808C07K 5/06026A61K 38/17A61K 38/08
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References
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Claims

Abstract

The invention relates to compounds exhibiting immuno-regulatory activity as determined by measuring the compound's ability to modulate production of NO by a cell. Preferred compounds include or consist of a sequence AAL AAQ AAG AAV wherein AAL is a substituted or unsubstituted non-polar amino acid selected from the group consisting of Ala and Leu; wherein AAQ is a substituted or unsubstituted amino acid selected from the group consisting of Gln, Pro, and Ala; wherein AAG is a substituted or unsubstituted amino acid Gly, and wherein AAV is a substituted or unsubstituted non-polar amino acid selected from the group consisting of Val and Ala. In one embodiment, the compound consists of a tripeptide selected from the group AQG, MTR, VVC, and mixtures thereof.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A composition comprising one or more purified or isolated peptides of the sequence AQGV (SEQ ID NO:2).

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