Stabilized aspirin compositions and method of preparation for oral and topical use

Abstract

Aspirin compositions for oral and topical use are stabilized by reaction with potassium hydroxide.

What is claimed is:  
     
       1. A medicinal drug which is mixed with a liquid carrier for oral or topical application to mammals to treat malodies conventionally treated using aspirin product, said drug being formed by combining a salicylic acid with potassium hydroxide in a water based solution to form potassium salicylic acid which is thereafter dehydrated to form a stabilized dry potassium salicylic acid. 
     
     
       2. The medicinal drug of  claim 1  wherein the salicylic acid is combined to a point of supersaturation in the water based solution. 
     
     
       3. The medicinal drug of  claim 1  mixed with water to form a dosing solution with a pH in the range of 8 to 10. 
     
     
       4. The medicinal drug of  claim 1  mixed with a water based carrier including a dermtologically acceptable lotion, cream, gel or ointment with a resulting pH which is compatible to mammalian skin. 
     
     
       5. The medicinal drug of  claim 1  wherein approximately one part by weight potassium hydroxide is combined in the water based solution with two parts by weight salicylic acid. 
     
     
       6. A medicinal drug which is mixed with a liquid carrier for oral application to mammals to treat malodies conventionally treated using aspirin product, said drug being formed by combining a acetylsalicylic acid with potassium hydroxide in a water based solution to form potassium acetylsalicylic acid which is thereafter dehydrated to form a stabilized dry potassium acetylsalicylic acid. 
     
     
       7. The medicinal drug of  claim 6  mixed with water to form a dosing solution with a pH in the range of 8 to 10. 
     
     
       8. The medicinal drug of  claim 6  mixed with a water based carrier including a dermtologically acceptable lotion, cream, gel or ointment with a resulting pH which is compatible to mammalian skin. 
     
     
       9. The medicinal drug of  claim 6  wherein approximately one part by weight potassium hydroxide is combined in the water based solution with two  approximately  1 . 3 parts by weight acetylsalicylic acid.