DNA sequence coding for protein C

Abstract

Genomic and cDNA sequences coding for a protein having substantially the same biological activity as human protein C are disclosed. Recombinant plasmids and bacteriophage transfer vectors incorporating these sequences are also disclosed.

We claim:  
     
       1. An isolated human DNA sequence which codes for a protein having substantially the same biological activity as human protein C, wherein said protein comprises a light chain as shown in FIG. 3 from amino acid number  1  to amino acid number  155 , and a heavy chain as shown in FIG. 3 from amino acid number  158  to amino acid number  419 . 
     
     
       2. An isolated DNA sequence comprising the sequence of FIG. 2, from bp 1 to bp 8972, which sequence codes for human protein C. 
     
     
       3. A bacterial plasmid or bacteriophage transfer vector comprising a cDNA sequence comprising the human protein C gene cDNA sequence.