USRE37262EExpiredUtility

Herbal compositions for treatment of gastrointestinal disorders

Assignee: CHINESE MEDICINES SCIENT CONSUPriority: Nov 2, 1998Filed: Jun 23, 2000Granted: Jul 3, 2001
Est. expiryNov 2, 2018(expired)· nominal 20-yr term from priority
A61K 36/00
64
PatentIndex Score
4
Cited by
4
References
33
Claims

Abstract

Herbal formulations are disclosed for the treatment of gastrointestinal disorders, in particular Irritable Bowel Syndrome (IBS). The compositions are formulated preferably with powdered herbs however combined extracts of herbs are also contemplated.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
       1. A composition comprising the herbs Ledebouriellae Sesloidis, Bupleurum Chinense, Artemesiae Capillaris, Fraxini, Plantaginis, Paeoniae Lactiflorae and Schizandrae. 
     
     
       2. A composition according to claim  1 , which is formulated with powdered herbs. 
     
     
       3. A composition according to claim  1 , which includes extracts of the herbs. 
     
     
       4. A composition according to claim  1 , in a capsule or table dosage form. 
     
     
       5. A composition according to claim  1 , further including pharmaceutically acceptable excipients, adjuvants, solvents, carriers, flavours, colourings or coatings. 
     
     
       6. A composition comprising at least two herbs selected from the group consisting of Codonoposis Pilosulae, Atractylodis Macrocephalae, Poriae Cocos and Olycyrrhizae Uralensis, any two herbs selected from the group consisting of Agastaches seu Pogostemi, Magnoliae Officinalis, Citri Reticulatae and Saussureae sue Vladimiriae, at least two herbs selected from the group consisting of Phellodendri, Coptidis, Coicis Lacluyma-jobi, Zingiberis Offinicinalis and Angelicae Dehuricae, and at least two herbs selected from the group consisting of Ledebouriellae Sesloidis, Bupleurum Chinense, Artemesiae Capillaris, Fraxini, Plantaginis, Paeoniae Lactiflorae and Schizandrae. 
     
     
       7. A composition according to claim  6 , which is formulated with powdered herbs. 
     
     
       8. A composition according to claim  6 , which includes extracts of the herbs. 
     
     
       9. A composition according to claim  6 , in a capsule or tablet dosage form. 
     
     
       10. A composition according to claim  6 , further including pharmaceutically acceptable excipients, adjuvants, solvents, carriers, flavours, colourings or coatings. 
     
     
       11. A composition comprising the herbs Codonoposis Pilosulae, Agastaches seu Pogostemi, Ledebouriellae Sesloidis, Coicis Lachyrmna-jobi, Bupleurum Chinense, Artemsiae Capillaris, Atractylodis Macrocephalae, Magrioliae Officinalis, Citri Reticulatae, Zingiberis Offinicinalis, Fraxini, Poriae Cocos, Angelicae Dehuricae, Plantaginis, Phellodendri, Glycyrrhizae Uralensis, Paeoniae Lactiflorae, Saussureae seu Vladimirae, Coptidis and Schizandrae. 
     
     
       12. A composition according to claim  11 , which is formulated with powdered herbs. 
     
     
       13. A composition according to claim  11 , which includes extracts of the herbs. 
     
     
       14. A composition according to claim  11 , in a capsule or tablet dosage form. 
     
     
       15. A composition according to claim  11 , further including pharmaceutically acceptable excipients, adjuvants, solvents, carriers, flavours, colourings or coatings. 
     
     
       16. A method of testing gastrointestinal disorders comprising administering to a subject requiring such treatment a theraeputically effective amount of a composition according to claim  1 , thereby treating the disorder. 
     
     
       17. A composition according to claim  16 , wherein the gastrointestinal disorder to be treated is Irritable Bowel Syndrome (IBS). 
     
     
       18. A method according to claim  16 , wherein the treatment is administered orally. 
     
     
       19. A method according to claim  16 , wherein the treatment is therapeutic or prophylactic and may be administered in a single bolus dose, multiple doses or via a slow release device. 
     
     
       20. A method of treating gastrointestinal disorders comprising administering to a subject requiring such treatment a composition according to claim  6 , thereby treating the disorder. 
     
     
       21. A method according to claim  20 , wherein the gastrointestinal disorder to be treated in Irritable Bowel Syndrome (IBS). 
     
     
       22. A method according to claim  20 , wherein the treatment is administered orally. 
     
     
       23. A method according to claim  20 , wherein the treatment is therapeutic or propylactic and may be administered in a single bolus dose, multiple doses or via a slow release device. 
     
     
       24. A method of treating gastrointestinal disorders including the administration to a subject requiring such treatment a composition according to claim  11 , thereby treating the disorder. 
     
     
       25. A method according to claim  24 , wherein the gastrointestinal disorder to be treated is Irritable Bowel Syndrome (IBS). 
     
     
       26. A method according to claim  24 , wherein the treatment is administered orally. 
     
     
       27. A method according to claim  24 , wherein the treatment is therapeutic or prophylactic and may be administered in a single bolus dose, multiple doses or via a slow release device. 
     
     
       28. A composition comprising  7 %  Dang Shen,  4 . 5   %  Huo Xiang,  3   %  Fang Feng,  7   %  Yi Yi Ren,  4 . 5   %  Chai Hu,  13   %  Yin Chen,  9   %  Bai Zhu,  4 . 5   %  Hou Po,  3   %  Chen Pi,  4 . 5   %  Pao Jiang,  4 . 5   %  Qin Pi,  4 . 5   %  Fu Ling,  2   %  Bai Zhi,  4 . 5   %  Che Qian Zi,  4 . 5   %  Huang Bai,  4 . 5   %  Zhi Gan Cao,  3   %  Bai Shao,  3   %  Mu Xiang,  3   %  Huang Lian and  7   %  Wu Wei Zi.    
     
     
       29. A composition comprising  3 %  Fang Feng,  4 . 5   %  Chai Hu,  13   %  Yin Chen,  4 . 5   %  Qin Pi,  4 . 5   %  Che Qian Zi,  3   %  Bai Shao, and  7   %  Wu Wei Zi.    
     
     
       30. A composition comprising any two herbs selected from the group consisting of Dang Shen (   7   %) , Bai Zhu  (   9   %) , Fu Ling  (   4 . 5   %)  and Zhi Gan Cao  (   4 . 5   %) ; in combination with any two herbs selected from the group consisting of Huo Xiang  (   4 . 5   %) , Hou Po  (   4 . 5   %) , Chen Pi  (   3   %) , and Mu Xiang  (   3   %) ; in combination with any two herbs selected from the group consisting of Huang Bai  (   4 . 5   %) , Huang Lian  (   3   %) , Yi Yi Ren  (   7   %) , Pao Jiang  (   4 . 5   %) , and Bai Zhi  (   2   %) ; in combination with any three herbs selected from the group consisting of Fang Fen  (   3   %) , Chai Hu  (   4 . 5   %) , Yin Chen  (   13   %) , Qin Pi  (   4 . 5   %) , Che Qian Zi  (   4 . 5   %) , Bai Shao  (   3   %)  and Wu Wei Zi  (   7   %) .    
     
     
       31. A composition comprising Dang Shen, Huo Xiang, Fang Feng, Yi Yi Ren, Chai Hu, Yin Chen, Bai Zhu, Hou Po, Chen Pi, Pao Jiang, Qin Pi, Fu Ling, Bai Zhi, Che Qian Zi, Huang Bai, Zhi Gan Cao, Bai Shao, Mu Xiang, Huang Lian and Wu Wei Zi.  
     
     
       32. A composition comprising Fang Feng, Chai Hu, Yin Chen, Qin Pi, Che Qian Zi, Bai Shoa, and Wu Wei Zi.  
     
     
       33. A composition comprising any two herbs selected from the group consisting of Dang Shen, Bai Zh, Fu Ling and Zhi Gan Cao; in combination with any two herbs selected from the group consisting of Huo Xiang, Hou Po, Chen Pi, and Mu Xiang; in combination with any two herbs selected from the group consisting of Huang Bai, Huang Lian, Yi Yi Ren, Pao Jiang, and Bai Zhi; in combination with any three herbs selected from the group consisting of Fang Fen, Chai Hu, Yin Chen, Qin Pi, Che Qian Zi, Bai Shao and Wu Wei Zi.

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