Separation of mannose by selective adsorption on zeolitic molecular sieves

Abstract

A process for the separation of mannose is disclosed which comprises the selective adsorption of same on certain types of zeolitic molecular sieves. The process is especially useful for separating mannose from glucose epimerization product or plant tissue hydrolyzate, using zeolites selected from the group consisting of BaX, BaY, SrY, NaY and CaY.

What is claimed is: 
     
       1. A selective adsorption process for the separation of mannose from a mixture containing mannose and at least one of glucose, arabinose, xylose and galactose which comprises contacting said mixture of mannose and at least one of glucose, arabinose, xylose and galactose at a pressure sufficient to maintain the system in the liquid phase with an adsorbent composition comprising at least one crystalline aluminosilicate zeolite selected from the group consisting of BaX, BaY, SrY, NaY, CaY and mixtures thereof, whereby mannose is selectively adsorbed thereon, removing the non-adsorbed portion of said mixture from contact with the zeolite adsorbent and desorbing the adsorbent therefrom by contacting said adsorbent with a desorbing agent and recovering the desorbed adsorbate. 
     
     
       2. A process in accordance with claim 1 wherein the temperature is from about 4' C. to about 150° C. 
     
     
       3. A process in accordance with claim 1 wherein the temperature is from about 20° C. to about 110° C. 
     
     
       4. A process in accordance with claim 1 wherein the desorbent is selected from the group consisting of water and mixtures thereof with alcohols or ketones. 
     
     
       5. A process in accordance with claim 1 wherein the desorbent is water. 
     
     
       6. A process in accordance with claim 1 wherein said mixture contains mannose and glucose. 
     
     
       7. A process in accordance with claim 1 wherein said mixture contains mannose and at least one of glucose, arabinose, xylose and galactose, and wherein said zeolite is BaY. 
     
     
       8. A process in accordance with claim 1 wherein said mixture comprises the hydrolysis product of plant tissue. 
     
     
       9. A process in accordance with claim 1 wherein said mixture comprises sodium-based sulfite liquor. 
     
     
       10. A process in accordance with claim 1 wherein said mixture comprises the epimerization product of glucose. 
     
     
       11. A process for separating mannose from the epimerization product of glucose which contains mannose and glucose, by selective adsorption which comprises contacting said product at a temperature of from about 4° C. to 150° C. and at a pressure sufficient to maintain the system in the liquid phase with an adsorbent composition comprising at least one crystalline aluminosilicate zeolite selected from the group consisting of BaX, BaY, SrY, NaY, CaY and mixtures thereof, whereby the mannose is selectively adsorbed thereon, removing the non-adsorbed portion of said product from contact with the zeolite adsorbent, and desorbing the mannose therefrom by contacting said adsorbent with a desorbing agent and recovering the desorbed mannose. 
     
     
       12. A process for separating mannose from plant tissue hydrolyzate by selective adsorption which comprises contacting said hydrolyzate at a temperature of from about 4° C. to 150° C. and a pressure sufficient to maintain the system in the liquid phase with an adsorbent composition comprising at least one crystalline aluminosilicate zeolite selected from the group consisting of BaX, BaY, SrY, NaY, CaY and mixtures thereof whereby the mannose is selectively adsorbed thereon, removing the non-adsorbed portion of said hydrolyzate from contact with the zeolite adsorbent, and desorbing the mannose therefrom by contacting said adsorbent with a desorbing agent and recovering the desorbed mannose. 
     
     
       13. A two-stage process for separating mannose from plant tissue hydrolyzate which contains mannose, glucose, arabinose, xylose and galactose, by selective adsorption which comprises contacting in a first stage said hydrolyzate at a temperature of from about 4° C. to 150° C. and at a pressure sufficient to maintain the system in the liquid phase with an adsorbent composition comprising a BaY crystalline aluminosilicate zeolite whereby a mixture of mannose and galactose are selectively adsorbed, removing the non-adsorbed portion of said hydrolyzate from contact with the zeolite adsorbent, desorbing the mixture of mannose and galactose therefrom by contacting said adsorbent with a desorbing agent; contacting in a second stage with said mixture at a temperature of from about 4° C. to 150° C. and at a pressure sufficient to maintain the system in a liquid phase with an adsorbent composition comprising a BaX crystalline aluminosilicate zeolite whereby mannose is selectively adsorbed thereon, removing the non-adsorbed portion of said mixture from contact with the zeolite adsorbent and desorbing the mannose therefrom by contacting said adsorbent with a desorbing agent and recovering the desorbed mannose. 
     
     
       14. A process for separating mannose from plant tissue hydrolyzate by selective adsorption which comprises contacting said hydrolyzate at a temperature of from about 4° C. to 150° C. and a pressure sufficient to maintain the system in the liquid phase with an adsorbent composition comprising a BaY zeolite whereby the mannose is selectively adsorbed thereon, removing the non-adsorbed portion of said hydrolyzate from contact with the zeolite adsorbent, and desorbing the mannose therefrom by contacting said adsorbent with a desorbing agent and recovering the desorbed mannose. .Iadd. 
     
     
       15.  A selective adsorption process for the separation of glucose from a mixture containing glucose and xylose which comprises contacting said mixture at a pressure sufficient to maintain the mixture in the liquid phase with an adsorbent composition comprising at least one crystalline aluminosilicate zeolite selected from the group consisting of BaY, NaX, CaY and mixtures thereof, whereby glucose is selectively adsorbed thereon, removing the non-adsorbed portion of said mixture from contact with the zeolite adsorbent and desorbing the adsorbent therefrom by contacting said adsorbent with a desorbing agent and recovering glucose. .Iaddend. .Iadd.16. A process in accordance with claim 15 wherein the temperature is from about 4° C. to about 150° C. .Iaddend. .Iadd.17. A process in accordance with claim 15 wherein the temperature is from about 20° C. to about 110° C. .Iaddend. .Iadd.18. A process in accordance with claim 15 wherein the desorbent is selected from the group consisting of water and mixtures thereof with alcohols or ketones. 
     
     
        .Iaddend. .Iadd.19.  A process in accordance with claim 15 wherein the desorbent is water. .Iaddend. .Iadd.20. A process in accordance with claim 15 wherein said zeolite is BaY. .Iaddend. .Iadd.21. A process in accordance with claim 15 wherein the crystalline aluminosilicate is CaY. .Iaddend. .Iadd.22. A process in accordance with claim 15 wherein said mixture comprises the hydrolysis product of plant tissue. .Iaddend. .Iadd.23. A process in accordance with claim 15 wherein said mixture 
     
     
        comprises sodium-based sulfite liquor. .Iaddend. .Iadd.24.  A selective adsorption process for the separation of galactose from a mixture containing xylose and galactose which comprises contacting said mixture at a pressure sufficient to maintain the mixture in the liquid phase with an adsorbent composition comprising at least one crystalline aluminosilicate zeolite selected from the group consisting of BaY, SrY, NaY, CaY and mixtures thereof, whereby galactose is selectively adsorbed thereon, removing the non-adsorbed portion of said mixture from contact with the zeolite adsorbent and desorbing the adsorbate therefrom by contacting said adsorbent with a desorbing agent and recovering galactose. .Iaddend. .Iadd.25. A process in accordance with claim 24 wherein the temperature is from about 4° C. to about 150° C. .Iaddend. .Iadd.26. A process in accordance with claim 24 wherein the temperature is from about 20° C. to about 110° C. .Iaddend. .Iadd.27. A process in accordance with claim 24 wherein the desorbent is selected from the group consisting of water and mixtures thereof with alcohols or ketones. .Iaddend. .Iadd.28. A process in accordance with claim 24 wherein the desorbent is water. .Iaddend. .Iadd.29. A process in accordance with claim 24 wherein said zeolite is BaY. .Iaddend. .Iadd.30. A process in accordance with claim 24 wherein said mixture comprises the hydrolysis product of plant tissue. .Iaddend. .Iadd.31. A process in accordance with claim 24 wherein said mixture comprises sodium-based sulfite liquor. .Iaddend. .Iadd.32. A selective adsorption process for the separation of galactose from a mixture containing glucose and galactose which comprises contacting said mixture at a pressure sufficient to maintain the mixture in the liquid phase with an adsorbent composition comprising at least one crystalline aluminosilicate zeolite selected from the group consisting of BaX, BaY, SrY, NaY, CaY and mixtures thereof, whereby galactose is selectively adsorbed thereon, removing the non-adsorbed portion of said mixture from contact with the zeolite adsorbent and desorbing the adsorbate therefrom by contacting said adsorbent with a desorbing agent and recovering the adsorbed galactose. .Iaddend. .Iadd.33. A process in accordance with claim 32 wherein the temperature is from about 4° C. to about 150° C. .Iaddend. .Iadd.34. A process in accordance with claim 32 wherein the temperature is from about 20° C. to about 110° C. .Iaddend. .Iadd.35. A process in accordance with claim 32 wherein the desorbent is selected from the group consisting of water and mixtures thereof with alcohols or ketones. .Iaddend. .Iadd.36. A process in accordance with claim 32 wherein the desorbent is water. .Iaddend. .Iadd.37. A process in accordance with claim 32 wherein said zeolite is NaY. .Iaddend. .Iadd.38. A process in accordance with claim 32 wherein said zeolite is BaY. .Iaddend. .Iadd.39. A process in accordance with claim 32 wherein the crystalline aluminosilicate is SrY. .Iaddend. .Iadd.40. A process in accordance with claim 32 wherein said mixture comprises the hydrolysis product of plant tissue. .Iaddend. .Iadd.41. A process in accordance with claim 32 wherein said mixture comprises 
     
     
        sodium-based sulfite liquor. .Iaddend. .Iadd.42.  A selective adsorption process for the separation of cellobiose from a mixture containing cellobiose and at least one of mannose, glucose, arabinose, galactose and xylose which comprises contacting said mixture at a pressure sufficient to maintain the mixture in the liquid phase with an adsorbent composition comprising at lease one crystalline aluminosilicate zeolite selected from the group consisting of KX, NaX, NaY, SrY and mixtures thereof, whereby cellobiose is selectively excluded from adsorption thereon, removing the non-adsorbed portion of said mixture from contact with the zeolite adsorbent and recovering the cellobiose. .Iaddend. .Iadd.43. A process in accordance with claim 42 wherein the temperature is from about 4° C. to about 150° C. .Iaddend. .Iadd.44. A process in accordance with claim 42 wherein the temperature is from about 20° C. to about 110° C. .Iaddend. .Iadd.45. A process in accordance with claim 42 wherein the desorbent is selected from the group consisting of water and mixtures thereof with alcohols or ketones. .Iaddend..Iadd.46. A process in accordance with claim 42 wherein the desorbent is water. .Iaddend. .Iadd.47. A process in accordance with claim 42 wherein zeolite is KX. .Iaddend. .Iadd.48. A process in accordance with claim 42 wherein said zeolite is NaX. .Iaddend. .Iadd.49. A process in accordance with claim 42 wherein the crystalline aluminosilicate is NaY. .Iaddend. .Iadd.50. A process in accordance with claim 42 wherein said crystalline 
     
     
        aluminosilicate is SrY. .Iaddend. .Iadd.51.  A process in accordance with claim 42 wherein said mixture comprises the hydrolysis product of plant tissue. .Iaddend.