Anti-microbial reaction product of #9 allantoin and formaldehyde

Abstract

.[.N-hydroxymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-N'-(hydroxymethyl)urea.]. .Iadd.A reaction product .Iaddend.prepared by the reaction of allantoin and formaldehyde is disclosed. The .[.compound.]. .Iadd.reaction product .Iaddend.exhibits activity against bacteria, mold and yeast and hence is useful as a preservative for products susceptable to microbial contamination.

What is claimed is: .[.1. A condensation product of formaldehyde and allantoin in the proportion of four moles of formaldehyde to one mole of allantoin having the structural formula: ##STR2## 
     
        .Iadd.2.  A reaction product formed by condensing formaldehyde and allantoin in the proportion of four moles of formaldehyde to one mole of allantoin, said reaction product exhibiting anti-microbial activity 
     
     
        against bacteria, yeast and mold. .Iaddend. .Iadd.3.  The product as claimed in claim 2, wherein said condensation is conducted in the presence of a basic catalyst. .Iaddend. .Iadd.4. The product as claimed in claim 2, wherein said condensation is conducted at elevated temperature. .Iaddend. .Iadd.5. The product as claimed in claim 4, wherein said condensation is conducted at reflux temperature. .Iaddend. .Iadd.6. The product as claimed in claim 2, wherein said condensation is conducted in an aqueous medium. .Iaddend.