Ether of n-propanol amine

Abstract

.[.Ethers.]. .Iadd.An ether .Iaddend.of n-propanolamine, preparation thereof and .[.their.]. .Iadd.its .Iaddend.use in treatment of cardiovascular conditions.

What we claim is:  .[.1. An ether of n-propanolamine having the formula.]. ##STR33## .[.wherein A is morpholino, pyrrolidino, piperidyl, and di-lower-alkyl amino, R is a straight or branched chain lower alkyl, or benzyl, Ar is aryl and Ar 1  is aryl or pyridyl, and pharmacologically acceptable 
     
        salts thereof..]. .[.2.  The ether of claim 1 in which A is pyrrolidino, R is isobutyl and Ar and Ar 1  are both phenyl, and the hydrochloride thereof..]. .[.3. The ether of claim 1 in which A is pyrrolidino, R is isobutyl, Ar is phenyl and Ar 1  is 2-pyridyl, and the acid fumarate thereof..]. .[.4. The ether of claim 1 in which A is diethylamino, R is an isobutyl and Ar and Ar 1  are both phenyl, and the acid fumarate thereof..]. .[.5. The ether of claim 1 in which A is morpholino, R is isobutyl and Ar and Ar 1  are both phenyl and the acid fumarate thereof..]. .[.6. The ether of claim 1 in which A is piperidyl, R is benzyl and Ar and Ar 1  are both phenyl and the hydrochloride thereof..]..Iadd. 7. An ether having the formula .Iaddend. ##STR34## .Iadd.and pharmaceutically acceptable acid addition salts thereof. 
     
     
        .Iaddend. .Iadd. 8.  An ether according to claim 7 wherein the acid addition salt is the hydrochloride or the acid fumarate. .Iaddend.