USRE29650EExpiredUtility

Phthalide penicillin ester intermediates

32
Priority: Jun 9, 1971Filed: Aug 18, 1977Granted: May 30, 1978
Est. expiryJun 9, 1991(expired)· nominal 20-yr term from priority
C07D 317/58Y02P20/55A61P 31/04C07D 499/00C07C 51/31C07D 307/88C07D 333/72
32
PatentIndex Score
2
Cited by
2
References
2
Claims

Abstract

.[.The.]. Phthalide ester of 6-[(D(-)α-aminophenylacetamido] penicillanic acid and intermediates therefor .[.are described.].. The phthalide penicillin ester is orally administrable to provide high serum concentrations of the .Iadd.free acid form of the .Iaddend..[.parent.]. penicillin. .[.This application is a division of application Ser. No. 259,560 filed June 5, 1972, now U.S. Pat. No. 3,860,579..]. .Iadd.

Claims

exact text as granted — not AI-modified
I claim: 
     
       1. A compound of the formula: ##STR14## wherein R is hydrogen or ##STR15## in which X is .[.NH 3   + ,.].  benzyloxycarbonylamino, N 3  or an enamine of the formula: ##STR16## wherein R 1  is lower alkyl, R 2  is H,   R 3  is lower alkyl, lower alkoxy or phenyl, or R 2  together with R 1  completes a fused 5- or 6 membered carbocyclic ring.   
     
     
       2. The compound of claim 1 in which R is hydrogen.

Join the waitlist — get patent alerts

Track USRE29650E — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.