Psoriasis treatment with mycophenolic acid

Abstract

Psoriasis is treated orally .[.and topically.]. with mycophenolic acid or its β-D-glucuronide.

I claim: 
     
       1. A method of treating psoriasis comprising the .Iadd.oral .Iaddend.administration to a human suffering from psoriasis .[.either orally or topically.]. of an effective amount for treating psoriasis of a compound of the formula: ##STR3## wherein M is hydrogen, sodium, potassium or ammonium and R is hydrogen or β-D-glucuronidyl. .[. 
     
     
       2.  A method according to claim 1 wherein a compound of the formula: ##STR4## wherein M is hydrogen, sodium, potassium or ammonium and R is hydrogen or β-D-glucuronidyl is applied topically to the psoriatic lesion in an amount from 3 mcg. to 300 mcg. per cm. 2  of lesion per day..]. 
     
     
       3.  A method according to claim 1 wherein from 1 to 10 gm. per day in divided doses of a compound of the formula: ##STR5## wherein M is hydrogen, sodium, potassium or ammonium and R is hydrogen or β-D-glucuronidyl is administered by the oral route to a human suffering from psoriasis.