3-Aminoindazole derivatives

Abstract

.Iadd.Pharmaceutical compositions having muscle relaxant and analgesic activity containing 3-aminoindazoles..Iaddend.

What is claimed is: 
     
       1. A .Iadd.pharmaceutical composition having analgesic and muscle relaxant activity, in dosage unit form, comprising a solid pharmaceutical carrier and from about 25 mg. to about 350 mg. of a .Iaddend.chemical compound of the class consisting of a free base and its nontoxic, pharmaceutically acceptable acid addition salts, the free base having the formula: ##SPC6## in which:   R is a member selected from the group consisting of halogen having an atomic weight of less than 80 and trifluoromethyl, said member being in a position β to the hetero ring;   R 1  is a member selected from the group consisting of hydrogen, lower alkyl and phenyl; and   R 2  and R 3  are members selected from the group consisting of hydrogen and lower alkyl.   
     
     
       2. A .Iadd.pharmaceutical composition having analgesic and muscle relaxant activity, in dosage unit form, comprising a solid pharmaceutical carrier and from about 25 mg. to about 350 mg. of a .Iaddend.chemical compound of the formula: ##SPC7## in which the CF 3  moiety is in a position β to the hetero ring.   
     
     
       3. .Iadd.A pharmaceutical composition of claim 2 containing .Iaddend. 3-amino-5-trifluoromethylindazole. 
     
     
       4. .Iadd.A pharmaceutical composition of claim 2 containing .Iaddend. 3-amino-6-trifluoromethylindazole. 
     
     
       5. .Iadd.A pharmaceutical composition having analgesic and muscle relaxant activity, in dosage unit form, comprising a solid pharmaceutical carrier and from about 25 mg. to about 350 mg. of a .Iaddend.chemical compound of the formula: ##SPC8## in which the Cl moiety is in a position β to the hetero ring.   
     
     
       6. .Iadd.A pharmaceutical composition of claim 5 containing .Iaddend. 3-amino-5-chloroindazole. .Iadd.7. A pharmaceutical composition of claim 5 containing .Iaddend. 3-amino-6-chloroindazole.