Implant comprising a biotoxic coating and method for the production thereof

Abstract

Disclosed is a method for producing an implant coating that has a defined toxicity. The method is characterized by the following steps: i. a sol is produced from a biotoxic solution containing precious metal ions and a precursor solution for a titanium oxide; ii. an implant is coated by applying the sol in a sol-gel process; iii. the coating is pyrolyzed and sintered without admitting any light, the precious metal ion concentration in the dried coating ranging from 10 to 60 percent relative to the total weight of the dried coating; and iv. at least subareas of the coating produced without admitting any light are illuminated in order to reduce the toxicity of the dried coating to a predetermined measure.

The invention claimed is: 
     
       1. A method of producing an implant with a coating whose toxicity can be adjusted, the method comprising the steps of:
 i. producing a sol from a biotoxically acting solution that contains precious metal ions, and a precursor solution for a titanium oxide; 
 ii. coating an implant by applying the sol with a sol-gel process; 
 iii. pyrolyzing and sintering the coating without admitting any light, so as to form a dried coating; wherein 
 
       the proportion of the precious metal ions in the dried coating being between 10 and 60% of a total mass of the dried coating,
 additionally comprising the steps of irradiating at least subareas of the coating for reducing the toxicity of the dried coating to a predetermined degree wherein the coating that has been produced without admitting any light is partially covered with an opaque template that has cutouts before being irradiated. 
 
     
     
       2. The method according to  claim 1 , wherein the irradiation step takes place while at least the irradiated subareas are heated at the same time. 
     
     
       3. The method according to  claim 1 , wherein the irradiation of the coating produced without admitting any light is carried out simultaneously on a multiplicity of spatially separate subareas. 
     
     
       4. The method according to  claim 1 , wherein, between the pyrolyzing and sintering without admitting any light and the irradiating of the coating that has been produced without admitting any light, a storage time without admitting any light is provided. 
     
     
       5. The method according to  claim 1 , wherein the irradiation of the coating that has been produced without admitting any light is carried out while heating at least the irradiated subareas to temperatures of between 80° C. and 250° C. 
     
     
       6. The method according to  claim 1 , wherein silver ions are used as the precious metal ions, and the silver percentage relative to the total mass of the dried coating is adjusted to between 30 and 60%. 
     
     
       7. The method according to  claim 1 , wherein the pyrolyzing step is performed at temperatures of about 250° C. without admitting any light and the sintering step is performed at temperatures of between 450° C. and 550° C. without admitting any light. 
     
     
       8. The method according to  claim 6 , additionally comprising stabilizing the sol containing silver ions by adding pyridine.