Method for treating premature ejaculation with a botulinum neurotoxin

Abstract

Methods for prolongation of climax time in a patient in need thereof are presented, as are methods for treating premature ejaculation by local administration of a Clostridial neurotoxin, such a botulinum neurotoxin, to the patient, are provided.

We claim: 
     
       1. A method for treating premature ejaculation in a patient in need thereof, the method comprising the step of locally administering by injection a  botulinum  neurotoxin to a penis of the patient, thereby treating premature ejaculation in the patient, wherein said local administration is to a frenulum of the penis. 
     
     
       2. The method of  claim 1 , wherein the  botulinum  neurotoxin is a  botulinum  neurotoxin type B and the  botulinum  neurotoxin type B is administered in an amount between 1 unit and about 10,000 units. 
     
     
       3. A method for treating premature ejaculation in a patient in need thereof, the method comprising the step of locally administering a  botulinum  neurotoxin type A to at least one location of a penis of the patient, thereby treating premature ejaculation in the patient, wherein the  botulinum  neurotoxin is administered to a prepuce a frenulum or glans of the penis, and further wherein an amount of  botulinum  neurotoxin type A administered to the penis is from about 1 unit to about 2500 units. 
     
     
       4. The method of  claim 3 , wherein the  botulinum  neurotoxin type A is administered to a prepuce of the penis. 
     
     
       5. The method of  claim 3 , wherein local administration of the  botulinum  neurotoxin is to a frenulum or prepuce.