US7711087B2ExpiredUtilityA1

Patient setup using tomosynthesis techniques

Assignee: VARIAN MED SYS INCPriority: Apr 7, 2006Filed: Apr 7, 2006Granted: May 4, 2010
Est. expiryApr 7, 2026(expired)· nominal 20-yr term from priority
A61N 5/1049A61B 8/543A61B 6/541A61B 6/032A61B 6/482A61N 2005/1061A61B 6/025A61B 6/5241
90
PatentIndex Score
69
Cited by
20
References
39
Claims

Abstract

A system for determining a position of an object includes an imaging system having a x-ray source and an imager, and a processor configured to obtain a tomosynthesis image of an object using the imaging system, and determine a position of the object using the tomosynthesis image. A method of determining a position of an object includes obtaining a tomosynthesis image of an object, and determining a coordinate of the object relative to a radiation machine using the tomosynthesis image. A device for determining a position of an object includes a processor for determining a coordinate of the object relative to a radiation machine using a tomosynthesis image. A method of determining a position of an object includes obtaining an image of an object, obtaining a reference image of the object, comparing the reference image with the image, and determining a coordinate of the object based at least in part on a result of the comparing, wherein the reference image has a plane that is parallel with a plane of the image.

Claims

exact text as granted — not AI-modified
1. A system for processing images, comprising:
 an imaging system having a x-ray source and an imager; and 
 a processor configured to 
 obtain a tomosynthesis image of an object for a phase of a first physiological cycle of a patient during a first time period using the imaging system, 
 receive a plurality of reference computed tomography (CT) images that are generated at respective phases of a second physiological cycle of the patient during a second time period, 
 select a CT image from the plurality of reference CT images, wherein the selected CT image has a corresponding phase that best matches with the phase associated with the tomosynthesis image, 
 compare the tomosynthesis image with a subset of the CT image, and 
 determine a position of the object based at least in part on a result of the comparison. 
 
     
     
       2. The system of  claim 1 , wherein the imager is configured to rotate over an angle that is between 5° and 45° to obtain a number of x-ray images. 
     
     
       3. The system of  claim 1 , wherein the source is configured to generate a number of x-ray images, wherein the number is a value that is between 5 and 100. 
     
     
       4. The system of  claim 1 , further comprising a treatment radiation source, wherein the position of the object is determined relative to a coordinate system associated with the treatment radiation source. 
     
     
       5. The system of  claim 1 , wherein the processor is further configured to perform a deblurring procedure to modify the tomosynthesis image. 
     
     
       6. The system of  claim 1 , wherein the subset of the CT image comprises a two dimensional CT image slice of the CT image. 
     
     
       7. The system of  claim 1 , wherein the processor is further configured to compare another tomosynthesis image with the subset of the CT image. 
     
     
       8. A method of determining a position of an object, at least part of the method implemented using a processor, the method comprising:
 obtaining an image of an object, wherein the image comprises a tomosynthesis image, wherein the object comprises a part of a patient, and the image is obtained for a phase of a first physiological cycle of the patient during a first time period; 
 receiving a plurality of reference computed tomography (CT) images that are generated at respective phases of a second physiological cycle of the patient during a second time period; 
 selecting one of the plurality of reference CT images having a corresponding phase that best matches the phase of the image; 
 obtaining a reference image of the object, the reference image having a plane that is parallel with a plane of the image, wherein the reference image comprises a subset of the selected one of the plurality of reference CT images; 
 comparing the reference image with the image; and 
 determining a coordinate of the object based at least in part on a result of the comparing. 
 
     
     
       9. The method of  claim 8 , wherein the obtaining the image comprises:
 obtaining a first x-ray image of the object using a x-ray source that is located at a first position; 
 moving the x-ray source from the first position to a second position; 
 obtaining a second x-ray image of the object using the x-ray source at the second position; and 
 processing the first and the second x-ray images. 
 
     
     
       10. The method of  claim 9 , wherein the first and the second x-ray images are processed to obtain a set of digital tomosynthesis images. 
     
     
       11. The method of  claim 10 , wherein the obtaining the image further comprises selecting one of the digital tomosynthesis images as the image, and the method further comprises:
 comparing another one of the digital tomosynthesis images with the reference image; 
 wherein the coordinate is determined based at least in part on a result of one of the comparing that indicates a better match. 
 
     
     
       12. The method of  claim 10 , wherein the obtaining the image further comprises deblurring one or more of the digital tomosynthesis images. 
     
     
       13. The method of  claim 8 , wherein the selected one of the plurality of reference CT images is a three-dimensional image, and wherein the reference image comprises a two-dimensional image determined from the selected one of the plurality of reference CT images. 
     
     
       14. The method of  claim 8 , wherein the coordinate of the object is expressed with reference to a coordinate system of a radiation machine. 
     
     
       15. The method of  claim 14 , wherein the radiation machine is selected from the group consisting of a treatment machine, a diagnostic machine, a simulator, an inspection machine, and a machine that is capable of performing a treatment procedure and a diagnostic procedure. 
     
     
       16. A method of determining a position of an object, at least part of the method implemented using a processor, the method comprising:
 obtaining a tomosynthesis image of an object, wherein the object comprises a patient, the tomosynthesis image is obtained for a phase of a first physiological cycle of the patient during a first time period; 
 receiving a plurality of three-dimensional reference computed tomography (CT) images that are generated at respective phases of a second physiological cycle of the patient during a second time period; 
 selecting one of the plurality of three-dimensional reference CT images having a corresponding phase that best matches the phase of the tomosynthesis image; 
 determining a two dimensional CT image from the selected one of the plurality of three-dimensional reference CT images; 
 determining a match between the tomosynthesis image and a two-dimensional CT image that is a subset of the three-dimensional CT image; and 
 determining a coordinate of the object relative to a radiation machine based at least in part on the determined match. 
 
     
     
       17. The method of  claim 16 , further comprising comparing another tomosynthesis image with the two-dimensional CT image. 
     
     
       18. The method of  claim 16 , wherein the obtaining the tomosynthesis image comprises:
 obtaining a first x-ray image of the object using a x-ray source that is located at a first position; 
 moving the x-ray source from the first position to a second position; 
 obtaining a second x-ray image of the object using the x-ray source at the second position; and 
 processing the first and the second x-ray images. 
 
     
     
       19. The method of  claim 18 , wherein the first and the second x-ray images are processed to obtain a set of digital tomosynthesis images. 
     
     
       20. The method of  claim 19 , wherein the obtaining the tomosynthesis image further comprises selecting one of the digital tomosynthesis images as the tomosynthesis image, and the method further comprises:
 comparing another one of the digital tomosynthesis images with the two-dimensional CT image to determine another match; 
 wherein the coordinate is determined based at least in part on one of the matches that indicates a better match. 
 
     
     
       21. The method of  claim 19 , further comprising deblurring one or more of the digital tomosynthesis images. 
     
     
       22. The method of  claim 16 , wherein the two dimensional CT image has an orientation relative to the object that corresponds with an orientation of the tomosynthesis image. 
     
     
       23. The method of  claim 16 , wherein the determining the coordinate comprises comparing the two dimensional CT image with the tomosynthesis image. 
     
     
       24. The method of  claim 16 , wherein the radiation machine is selected from the group consisting of a treatment machine, a diagnostic machine, a simulator, and a machine that is capable of performing a treatment procedure and a diagnostic procedure. 
     
     
       25. The method of  claim 16 ,
 wherein the tomosynthesis image is obtained by receiving a plurality of x-ray images and processing the x-ray images using a back projection technique. 
 
     
     
       26. The method of  claim 25 , wherein the tomosynthesis image is obtained by performing a filtering procedure. 
     
     
       27. The method of  claim 26 , wherein the filtering procedure is performed after the back projection procedure is performed. 
     
     
       28. The method of  claim 25 , wherein the number of x-ray images is less than that associated with a complete set for forming a volumetric CT image. 
     
     
       29. A method for use in a radiation treatment procedure, at least part of the method implemented using a processor, the method comprising:
 obtaining a first tomosynthesis image of an object; 
 determining a first two dimensional coordinate of the object using the first tomosynthesis image; 
 obtaining a second tomosynthesis image of the object; 
 determining a second two dimensional coordinate of the object using the second tomosynthesis image; and 
 determining a three dimensional coordinate of the object using a processor based on the first and second two dimensional coordinates, wherein the act of determining the three dimensional coordinate is performed during a radiation treatment section; 
 wherein the act of determining the three dimensional coordinate based at least in part on the first and the second two dimensional coordinates is performed during a delivery of a treatment radiation beam or between deliveries of treatment radiation beam pulses to treat a target at an isocenter. 
 
     
     
       30. The method of  claim 29 , wherein the obtaining the first tomosynthesis image comprises:
 obtaining a first x-ray image of the object using a x-ray source that is located at a first position; 
 moving the x-ray source from the first position to a second position; 
 obtaining a second x-ray image of the object using the x-ray source at the second position; and 
 processing the first and the second x-ray images. 
 
     
     
       31. The method of  claim 30 , wherein the first and the second x-ray images are processed to obtain a set of digital tomosynthesis images. 
     
     
       32. The method of  claim 31 , wherein the obtaining the first tomosynthesis image further comprises selecting one of the digital tomosynthesis images as the first tomosynthesis image. 
     
     
       33. The method of  claim 31 , further comprising deblurring one or more of the digital tomosynthesis images. 
     
     
       34. The method of  claim 29 , wherein the determining the three dimensional coordinate of the object comprises performing a triangulation procedure using the first and the second two dimensional coordinates. 
     
     
       35. The method of  claim 29 , further comprising controlling a treatment radiation source or a collimator based at least in part on the three dimensional coordinate that is determined using the first and the second tomosynthesis images respectively. 
     
     
       36. The method of  claim 29 , further comprising tracking a movement of the object during the radiation treatment session based at least in part on the three dimensional coordinate. 
     
     
       37. A device for use in a radiation treatment procedure, comprising:
 a processor configured for:
 obtaining a first tomosynthesis image of an object, 
 determining a first two dimensional coordinate of the object using the first tomosynthesis image, 
 obtaining a second tomosynthesis image of the object, 
 determining a second two dimensional coordinate of the object using the second tomosynthesis image, and 
 determining a three dimensional coordinate of the object during a radiation treatment session based at least in part on the first and the second two dimensional coordinates; and 
 a memory for storing the first and second tomosynthesis images; 
 wherein the processor is configured to determine the three dimensional coordinate during a delivery of a treatment radiation beam or between deliveries of treatment radiation beam pulses to treat a target at an isocenter. 
 
 
     
     
       38. The device of  claim 37 , wherein the processor is configured to control a treatment radiation source or a collimator based at least in part on the three dimensional coordinate that is determined using the first and the second tomosynthesis images respectively. 
     
     
       39. The device of  claim 37 , wherein the processor is configured to track a movement of the object during the radiation treatment session based at least in part on the three dimensional coordinate.

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