Topical treatment for dyshidrosis (pompholyx) and dry skin disorders

Abstract

A topical herbal formulation for preventing and/or treating dyshidrosis (pompholyx), non-responsive to topical steroids. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders. The active ingredients within the formula include a combination of dry, aqueous, acid and alcohol extracts of black walnut hull ( Juglans Nigra ), wormwood ( Artemisia Absinthium ), tumeric rhizome ( Curcuma Longa ), garlic ( Allium sativum ), chamomile ( Matricaria Chamomile ), licorice root ( Glycyrrhiza Glabra ), St Johns wort ( Hypericum perforatum ), aloe vera, niacin and herbal anti-bacterial agents.

1. A topical skin care composition useful for treating dyshidrosis (pompholyx) and dry skin disorders, said composition comprising a therapeutically effective amount of:
 a) black walnut, wormwood, tumeric, garlic, wherein said garlic can be optionally substituted with propolis; 
 b) two or more antibacterial/anti-inflammatory herbs selected from the group consisting of St. Johns wort, licorice, chamomile, clove, nutmeg, ginger, and myrrh; 
 c) Aloe vera, alone or in combination with a dermatologically acceptable carrier, and; 
 d) niacin, wherein said niacin further comprises niacinamide, and nicotinic acid. 
 
     
     
       2. The composition according to  claim 1 , wherein said black walnut comprises an extract derived from  Juglans nigra , constituting between 0.5%-90% by weight of the total weight of the composition. 
     
     
       3. The composition according to  claim 1 , wherein said wormwood comprises an extract derived from  Artemisia absinthium , constituting between 0.5%-90% by weight of the total weight of the composition. 
     
     
       4. The composition according to  claim 1 , wherein said turmeric comprises extract derived from  Curcuma longa , constituting between 0.5% to 90% by weight of the total weight of the composition. 
     
     
       5. The composition according to  claim 1 , wherein said garlic comprises an extract derived from  Allium sativum , constituting between 0.75 to 70% by weight of the total weight of the composition. 
     
     
       6. The composition according to  claim 5 , wherein said garlic further embodies a physical form of one or more selected from the group consisting of maccrated, minced, diced, dried, pulverized, powdcred, deodorized and shredded. 
     
     
       7. The composition according to  claim 1 , wherein said propolis is combined with garlic, constituting collectively between 0.75 to 70% by weight of the total weight of the composition. 
     
     
       8. The composition according to  claim 1 , wherein said St. Johns wort comprises an extract derived from  Hypericum perforatum , constituting between 0.5 to 25% by weight of the total weight of the composition. 
     
     
       9. The composition according to  claim 1 , wherein said licorice comprises an extract derived  Glycyrrhiza glabra , genus, constituting between 0.5 to 25% by weight of the total weight of the composition. 
     
     
       10. The composition according to  claim 1 , wherein said chamomile comprises an extract derived from  Matricaria chamomile , constituting between 0.5 to 25% by weight of the total weight of the composition. 
     
     
       11. The composition according to  claim 1 , wherein said clove, nutmeg, ginger, and myrrh comprises extracts derived from  Syzygium aromaticum, Myristica fragans, Zingiber officinale, Commiphora molmol , respectively, wherein a combination of the two or more of these herbs constitute between 0.5 to 25% by weight of total weight of the composition. 
     
     
       12. The composition according to  claim 1 , wherein said Aloe vera alone or combined with a dermatologically acceptable carrier constitutes between 5-95% by weight of the total weight of the composition. 
     
     
       13. The composition according to  claim 12 , wherein said dermatologically acceptable carrier is comprises one or more selected from the group consisting of surfactarits, binders, emulsiliers, bulking agents, starches, additives, diluents, stabilizers, preservatives, emollients, foaming agents, gels, sweeteners, thickeners, vehicles, coloring agents, fragrances, solvents, moisturizers, lubricants, deodorizers and buffers. 
     
     
       14. The composition according to  claim 13 , wherein said dermatologically acceptable carrier is in a form of at least one selected from the group consisting of a suspension, solution, dispersion, lotion, liquid, gel, stick, capsule, foam, cream, pack, paste, coated glove or sock, salve, spray, aerosol, ointment, sponge, gel cap, granule, medicated bandage, mnedicated gauze, microparticles, nanospheres, microspheres, wipes, oil, powder and bio-delivery system. 
     
     
       15. The composition according to  claim 1 , wherein said dermatologically acceptable carrier comprises at least one selected from a group consisting of purified water, lanolin, lanolin alcohols, alcohols, vitamins, methylparaben, ethylparaben, butylparaben propylparaben, glycerin, vegetable oils, polysorbate, propylene glycol, para-aminobenzoie acid, mineral oil, carbomer, phospholipids, flour, starch, sorbitan laurate, carboxylic acids, triethanolamine, talc, titanium dioxide, antioxidants, gums, petrolatum, jojoba oil, isopropyl myristate, cetyl palmitate, sorbitan stearate, acids, base, cellulose, simethicone, butylated hydroxyanisole, butylated hydroxytoluene, glycol distearate, cetearyl alcohol, sorbitol, glyceryl stearate, cetearyl octanoate, dimethicone, wax, ethylenediaminetetraacetic acid, sodium lauryl sulfate, glyceryl dilaurate, quarteriurn-15, calcium sulfate, calcium chloride, metal salts, gelatin and imidazolidinyl urea. 
     
     
       16. The composition according to  claim 2 , wherein said black walnut constitutes about 9% by weight of the total weight of the composition. 
     
     
       17. The composition according to  claim 3 , wherein said wormwood constitutes about 9% by weight of the total weight of the composition. 
     
     
       18. The composition according to  claim 4 , wherein said turmeric
 constitutes about 7% by weight of the total weight of the composition. 
 
     
     
       19. The composition according to  claim 5 , wherein said garlic constitutes about 10% by weight of the total weight of the composition. 
     
     
       20. The composition according to  claim 7 , wherein said propolis is
 combined with garlic and constitutes collectively about 10% by weight of the total weight of the composition. 
 
     
     
       21. The composition according to  claim 8 , wherein said St. Johns wort constitutes about 3% by weight of the total weight of the composition. 
     
     
       22. The composition according to  claim 9 , wherein said licorice constitutes about 3% by weight of the total weight of the composition. 
     
     
       23. The composition according to  claim 10 , wherein said chamomile
 constitutes about 2% by weight of the total weight of the composition. 
 
     
     
       24. The composition according to  claim 11 , wherein said combination
 of at least two or more of clove, nutmeg, ginger, and myrrh constitute collectively about 2% by weight of the total weight of the composition. 
 
     
     
       25. The composition according to  claim 12 , wherein said Aloe vera alone or combined with a dermatologically acceptable carrier constitutes about 54% by weight of the total weight of the composition. 
     
     
       26. The composition according to  claim 1 , wherein said niacin niacinamide, and nicotinic acid constitutes about 1% by weight of the total weight of the composition.