US7344713B1ExpiredUtility
Decreased fat absorption with an anti-lipase antibody
Individually held — no corporate assignee on recordPriority: Jul 7, 1997Filed: Jul 7, 1997Granted: Mar 18, 2008
Est. expiryJul 7, 2017(expired)· nominal 20-yr term from priority
Inventors:Julio Pimentel
A61P 3/04C07K 16/02A61P 3/00C07K 16/40A61K 38/00
36
PatentIndex Score
4
Cited by
27
References
7
Claims
Abstract
A method for the decrease of fat absorption in a mammal, wherein the animal is orally fed an antibody produced against lipase, an enzyme which is required for fat absorption.
Claims
exact text as granted — not AI-modified1. A method for decreasing mammalian absorption of fats by the gastrointestinal tract said method comprising inhibiting lipase activity in the mammal, said method comprising the step of: orally administering to the mammal anti-lipase avian antibodies that decrease activity of said lipase relative to a control, wherein said control does not receive said avian antibodies, wherein said inhibiting decreases the breaking down of ingested fats thereby decreasing the absorption of said fats by the gastrointestinal tract.
2. The method of claim 1 , wherein prior to the step of administering to the mammal said avian antibody, said avian antibody is produced in avian eggs.
3. The method of claim 1 , wherein prior to the step of administering said avian antibody, said avian antibody is first freeze dried or spray dried.
4. The method of claim 1 , wherein said avian antibody is fed in a powder form or in liquid form admixed in whole egg or yolk.
5. The method of claim 1 , wherein said avian antibody is fed in a liquid form.
6. A method of reducing weight gain in a mammal by decreasing mammalian absorption of fats in gastrointestinal tract by inhibiting lipase activity in said mammal, said method comprising the step of: orally administering to said mammal an amount of antilipase avian antibodies effective to decrease activity of said lipase relative to control, wherein said control does not receive said avian antibodies, wherein said inhibiting decreases the breaking down of ingested fats thereby decreasing the absorption of said fats by the gastrointestinal tract and reducing weight gain in said mammal.
7. The method of claim 6 wherein said step of orally administering comprises orally administering said antilipase antibody in combination with the mammal's feed.Join the waitlist — get patent alerts
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