US7196181B1ExpiredUtility

Sequences encoding novel human thyroid peroxidase proteins and polypeptides

31
Assignee: QUEST DIAGNOSTICS INVEST INCPriority: Jan 30, 1990Filed: Jun 7, 1995Granted: Mar 27, 2007
Est. expiryJan 30, 2010(expired)· nominal 20-yr term from priority
Inventors:Basil Rapoport
C12Q 2600/156C07K 16/40C12N 9/0065C12Q 2600/158A61P 37/00C12Q 1/6883A61K 38/00
31
PatentIndex Score
3
Cited by
78
References
4
Claims

Abstract

Disclosed are DNA sequences encoding novel human thyroid peroxidase proteins and polypeptides capable of being secreted from cells, vectors comprising the sequences, and cells transformed with the vectors.

Claims

exact text as granted — not AI-modified
1. A recombinant DNA sequence encoding a human thyroid peroxidase which is secreted from a cell, wherein the DNA has the sequence of SEQ ID NO: 2 with a stop codon at nucleotides. 
     
     
       2. A recombinant DNA sequence consisting of nucleotides 1-2628 of SEQ ID NO: 2. 
     
     
       3. A recombinant DNA sequence consisting of nucleotides 85-2628 of SEQ ID NO: 2. 
     
     
       4. A recombinant DNA sequence encoding a human thyroid peroxidase that consists of amino acids 1 to 848 of the amino acid sequence shown in SEQ ID NO: 3.

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