US6316252B1ExpiredUtility

Biotherapeutic delivery system

Assignee: WISCONSIN ALUMNI RES FOUNDPriority: Dec 17, 1998Filed: Dec 17, 1998Granted: Nov 13, 2001
Est. expiryDec 17, 2018(expired)· nominal 20-yr term from priority
Y10S530/826C07K 14/005C12N 15/87C12N 2710/16722C07K 2319/00
22
PatentIndex Score
0
Cited by
15
References
4
Claims

Abstract

Disclosed herein are fusion proteins, nucleotide sequences for creating them, and vectors containing the nucleotide sequences. The fusion proteins have a bovine herpesvirus protein linked to a biotherapeutic protein or reporter protein. They rapidly spread biotherapeutic or reporter protein throughout mammalian cells.

Claims

exact text as granted — not AI-modified
We claim:  
     
       1. A peptide comprising SEQ ID NO: 2 bovine herpesvirus protein linked to a non-bovine reporter protein. 
     
     
       2. The peptide of claim  1  wherein the non-bovine protein is a fluorescent protein. 
     
     
       3. A nucleotide sequence coding for SEQ ID NO: 2 bovine herpesvirus protein linked to a non-bovine reporter protein. 
     
     
       4. A nucleotide vector comprising a vector backbone and a nucleotide sequence coding for SEQ ID NO: 2 bovine herpesvirus protein linked to a non-bovine reporter protein.

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