US5622845AExpiredUtility

Fermentation method for producing norleucine

38
Assignee: UPJOHN COPriority: Feb 17, 1988Filed: Jun 6, 1995Granted: Apr 22, 1997
Est. expiryFeb 17, 2008(expired)· nominal 20-yr term from priority
Inventors:David P. BrunnerGary C. HarbourRichard J. KirschnerJames F. PinnerRobert L. Garlick
Y10S435/849C12N 1/20C12P 1/00C07K 14/61C12P 13/04
38
PatentIndex Score
8
Cited by
49
References
1
Claims

Abstract

The present invention provides an inexpensive fermentation medium for growing microorganisms. Also provided are fermentation media and methods for producing norleucine by growing E. coli thereon, fermentation media and methods for incorporating norleucine into polypeptides expressed by microorganisms grown thereon, and fermentation media and methods for preventing the incorporation of norleucine into polypeptides expressed by microorganisms grown thereon. Also provided are bovine somatotropin analogs.

Claims

exact text as granted — not AI-modified
We claim: 
     
       1. A method for producing norleucine comprising growing E. coli on a fermentation medium having a low concentration of amino acids and then isolating the norleucine produced by said E. coli.

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