Analgesic method

Abstract

Disclosed herein are analgesic copper coordination compounds and a process for using them in the treatment of analgesia in animal bodies. The copper coordination compounds utilized are the reaction products of copper salts with: 1. carboxylic acids or their alkaline earth salts; 2. aromatic carboxylic acids or their alkaline earth salts; 3. heterocyclic carboxylic acids or their alkaline earth salts; 4. amino acids or their alkaline earth salts; 5. anthranilic acids or their alkaline earth salts; 6. salicylic acids or their alkaline earth salts; 7. acetylsalicylates or their alkaline earth salts; 8. arylacetic acids or their alkaline earth salts; 9. disubstituted aminodithiocarbamates, and mixtures of any of the above. The process disclosed comprises administering to animals, orally or parenterally, in controlled dosages, the aforementioned copper coordination compounds.

Having thus described my invention, I claim: 
     
       1. A method of treating algesia in a patient not suffering from inflammation comprising administering to said patient a therapeutically effective amount of an organic coordination compound of copper, said compound comprising the reaction product of copper and an amino acid or alkaline earth salt thereof. 
     
     
       2. The method of claim 1 wherein the copper coordination compound is administered in an amount of 2 to 165 mg. per kilogram of body weight. 
     
     
       3. The method of claim 2 wherein said compound is the reaction product of a compound selected from the group consisting of cupric chloride and cupric acetate and an amino acid or alkaline earth salt thereof. 
     
     
       4. The method of claim 3 where said amino acid is tryptophan. 
     
     
       5. The method of claim 3 where said amino acid is lysine. 
     
     
       6. The method of claim 4 wherein said compound is administered orally or parenterally. 
     
     
       7. The method of claim 5 wherein said compound is administered orally or parenterally.