US4929640AExpiredUtility

Medicaments intended for combined use in the improvement of lymphocyte function

Individually held — no corporate assignee on recordPriority: Apr 4, 1988Filed: Apr 4, 1988Granted: May 29, 1990
Est. expiryApr 4, 2008(expired)· nominal 20-yr term from priority
Inventors:R. Arnold Smith
A61K 33/24A61K 31/48A61K 31/525A61K 31/475A61K 31/57
22
PatentIndex Score
0
Cited by
7
References
12
Claims

Abstract

A new composition, useful as a medicament, contains ascorbate, preferably as metallic salt(s), in combination with a dopamine agonist such as bromocriptine, with the ratio by weight of ascorbate to bromocriptine being 400:1 or greater. This combination, believed to act through stimulation of pituitary production of somatotropin, has a significant ability to stimulate enhanced lymphocyte function. Other useful dopamine agonists include lergotrile and pergolide.

Claims

exact text as granted — not AI-modified
I claim: 
     
       1. A method for stimulating enhanced lymphocyte function in human beings requiring such treatment comprising administering to a said human being one part by weight of a dopamine agonist compound selected from the group consisting of bromocriptine, lergotrile and pergolide and at least 400 parts by weight of an ascorbate. 
     
     
       2. The method as defined in claim 1 wherein the dopamine agonist is administered in an amount ranging from about 0.615 to 5.0 milligrams. 
     
     
       3. The method as defined in claim 1 wherein the dopamine agonist is bromocriptine. 
     
     
       4. The method as defined in claim 1 wherein the ascorbate is sodium ascorbate. 
     
     
       5. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from inflammatory mesenchymal disorders. 
     
     
       6. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from auto-immune mediated inflammatory glandular disorders. 
     
     
       7. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from auto-immune epidermal disorders. 
     
     
       8. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from decreased immune resistance to chronic viral infections. 
     
     
       9. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from recurrent migraine headaches. 
     
     
       10. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from loss of physical strength, loss of energy and psychological depression associated with disturbances of somatotropin secretion. 
     
     
       11. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from severe allergies. 
     
     
       12. The method of claim 1 wherein the stimulated enhanced lymphocyte function is used in the treatment of humans suffering from drug abuse.

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