US4697002AExpiredUtility

Calcitonin gene related peptide analogs with amino acid subdstituents at the penultimate position 36

67
Individually held — no corporate assignee on recordPriority: Dec 23, 1985Filed: Dec 23, 1985Granted: Sep 29, 1987
Est. expiryDec 23, 2005(expired)· nominal 20-yr term from priority
Inventors:Tomas Kempe
A61K 38/00C07K 14/57527
67
PatentIndex Score
31
Cited by
3
References
5
Claims

Abstract

New calcitonin gene related peptide analogs (CGRP) are disclosed which have biological activity of the same type as known calcitonin gene related peptides and which have an amino acid substituent at position 36 or the penultimate position instead of the naturally occurring amino acid--Ala.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. [Ser 36  ] human calcitonin gene-related peptide. 
     
     
       2. [Hse 36  ] human calcitonin gene-related peptide. 
     
     
       3. [Thr.sup.∓ ] human calcitonin gene-related peptide. 
     
     
       4. [Asp 36  ] human calcitonin gene-related peptide. 
     
     
       5. [Asn 36  ] human calcitonin gene-related peptide.

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