Imidazo[1,2-c][1,3]benzodiazepines

Abstract

5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines, for example compounds of the formula ##STR1## in which e.g., R 1 , R 2 and R 4 are hydrogen, R 3 is methyl and C n H 2n is CH 2 CH 2 , have neuroleptic and/or antihistaminic activity. The synthesis, pharmaceutical compositions and methods of treatment utilizing such compounds are described.

What is claimed is: 
     
       1. A compound of the formula ##STR9## wherein each of R 1  and R 2  are hydrogen, lower alkyl, cyano, carboxy, lower alkoxycarbonyl or carbamoyl; n represents the integer 3; R 3  is hydrogen, lower alkyl, lower alkoxycarbonyl or hydroxy lower alkyl of 2 to 4 carbon atoms; R 4  represents hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen or trifluoromethyl; R 5  represents hydrogen; and R 6  and R 7  represent hydrogen or lower alkyl; and N-oxide; or a pharmaceutically acceptable salt thereof. 
     
     
       2. 5-(4-methyl-1-homopiperazinyl)-11H-imidazo[1,2-c][1,3]benzodiazepine.