US4329453AExpiredUtility

Cephalosporin antibiotic

77
Assignee: GLAXO GROUP LTDPriority: Oct 2, 1979Filed: Sep 9, 1980Granted: May 11, 1982
Est. expiryOct 2, 1999(expired)· nominal 20-yr term from priority
Inventors:Alastair C. BrodieLewis A. Wetherill
A61P 31/04C07D 501/46
77
PatentIndex Score
25
Cited by
1
References
1
Claims

Abstract

(6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate in the form of its crystalline pentahydrate. This pentahydrate has a well defined crystalline structure and exhibits good stability on storage. The pentahydrate exhibits excellent antibiotic activity, particularly against organisms which are normally difficult to combat with β-lactam antibiotics.

Claims

exact text as granted — not AI-modified
We claim: 
     
       1. (6R,7R)-7-[(Z)-2-(2-Aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate pentahydrate.

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