Dephosphorylation of skim milk, ultra-filtered milk or micellar casein isolate
Abstract
The invention relates to a process for dephosphorylation of skim milk, ultra-filtered milk (UF milk) or micellar casein isolate (MCI) comprising (i) acidification of a skim milk, UF milk or MCI preferably not lower than pH 6.0, preferably between 6.0 and 6.7, (ii) cooling the acidified skim milk, UF milk or MCI to the temperature between 0° C. and 15° C., (iii) adding gluconate and/or maleate to the cooled skim milk, UF milk or MCI and, (iv) washing the skim milk, UF milk or MCI, to remove phosphorus, thus dephosphorylating the skim milk, UF milk or MCI, preferably to an extent that the total phosphorous content of the skim milk, UF milk or MCI is reduced with at least 20%, preferably 20-40%, more preferably 30-40% compared to the material provided to step (i). The invention also relates to dephosphorylated MPC, MPI or MCI obtainable by the process of the invention, and to a liquid heat-sterilized enteral nutritional composition comprising 2.0-3.0 kcal/ml wherein 16-35 en % is provided by protein, the combination of caloric content and relative protein caloric content selected such that there is 10-18 g/100 ml protein, preferably 12-18 g/100 ml protein in the composition, wherein the protein comprises micellar casein (MC), whey protein (WP) and optionally caseinate (CAS), wherein there is at least 70 wt % MC and less than 15 wt % WP, based on total protein content, and wherein the composition has a total amount of phosphorous less than 192 mg/100 ml and/or 30-80 mg/100 kcal, preferably at least 30-80 mg/100 kcal, most preferably less than 192 mg/100 ml and 30-80 mg/100 kcal.
Claims
exact text as granted — not AI-modified1 .- 13 . (canceled)
14 . A process for dephosphorylation of milk protein concentrate (MPC), milk protein isolate (MPI) or micellar casein isolate (MCI) comprising;
(i) acidification of a MPC, MPI or MCI not lower than pH 6.0, (ii) cooling the acidified MPC, MPI or MCI to the temperature between 0° C. and 15° C., (iii) adding gluconate and/or maleate to the cooled MPC, MPI or MCI and,
washing the MPC, MPI or MCI, to remove phosphorus, wherein washing is carried out using microfiltration and/or diafiltration, thus dephosphorylating the MPC, MPI or MCI compared to the material provided to step (i),
wherein the maleate chelator is not hydrogen maleate salt.
15 . The process according to claim 14 , wherein the gluconate and/or maleate chelator is sodium gluconate, potassium gluconate, disodium maleate and/or dipotassium maleate.
16 . A dephosphorylated milk protein concentrate (MPC), milk protein isolate (MPI) or micellar casein isolate (MCI), the MPC, MPI or MCI comprising (added) gluconate and/or maleate, wherein the maleate is not hydrogen maleate salt, the MPC, MPI or MCI
having a total phosphorous content of less than 15.0 mg total phosphorous per gram protein, having a protein content of at least 60 wt %, and obtainable by the process according to claim 14 .
17 . A liquid heat-sterilized enteral nutritional composition comprising a caloric content of 2.0-3.0 kcal/ml and a relative protein caloric content defined as 16-35 en % is provided by protein, wherein the caloric content and the relative protein caloric content are preferably selected such that there is 10-18 g/100 ml protein protein in the composition, wherein the protein comprises micellar casein (MC), whey protein (WP) and optionally caseinate (CAS), wherein there is at least 70 wt % MC and less than 15 wt % WP, based on total protein content, and wherein the composition has a total amount of phosphorous less than 192 mg/100 ml and/or 30-80 mg/100 kcal,
and wherein the MC is provided (i) by the dephosphorylated MPC, MPI or MCI comprising (added) gluconate and/or maleate, wherein the maleate is not hydrogen maleate salt, the MPC, MPI or MCI
having a total phosphorous content of less than 15.0 mg total phosphorous per gram protein,
having a protein content of at least 60 wt %, or
(ii) by the MPC, MPI or MCI obtainable by the process of claim 14 .
18 . The liquid composition according to claim 17 , wherein the total amount of phosphorous is 30-72 mg/kcal (i.e. at least 10% below the foods for special medical purposes (FSMP) maximum), preferably 30-64 mg/kcal (i.e. at least 20% below the FSMP maximum).
19 . The liquid composition according to claim 17 , wherein the protein provides 16% to 32% of the total energy content of the composition, more preferably 18% to 30 en %, even more preferably 20% to 28 en %, preferably in combination with a caloric content of 2.2-2.6 kcal/ml.
20 . The liquid composition according to claim 17 , wherein the amount of protein is between 12 and 18 g/100 ml.
21 . The liquid composition according to claim 17 , wherein the weight ratio of micellar casein to caseinate ranges from 90:10 to 75:25.
22 . The liquid composition according to claim 17 , wherein the amount of whey protein is less than 10 wt % based on total protein.
23 . The liquid composition according to claim 17 , further comprising at least 2 mineral levels for Na, K, Cl, Ca and Mg within the ranges (mg/100 kcal) according to the table below:
FSMP (min-max per 100 kcal)
Na (mg)
30-175
K (mg)
80-295
Cl (mg)
30-175
Ca (mg)
35-175
Mg (mg)
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