Acellular dermal matrix sheet allografts having specialized mesh patterns

Abstract

There is disclosed a packaged allograft implant configured for implantation in a human recipient. In an embodiment, the packaged allograft implant includes an acellular dermal matrix sheet having a top surface and a bottom surface in opposition to one another, a perimeter surrounding the top surface and the bottom surface, and a thickness extending between the top surface and the bottom surface. The packaged allograft implant further includes a mesh pattern extending across at least a portion of the top surface and the bottom surface of the acellular dermal matrix sheet, the mesh pattern providing through-holes extending between the top surface and the bottom surface of the acellular dermal matrix sheet, and the mesh pattern having a plurality of mesh lines extending in a first direction and a second direction. The first direction and the second direction are orthogonal to one another so as to allow a given amount of stretch in each of the first direction and the second direction. Other embodiments are also disclosed.

1 . (canceled) 
     
     
         2 . The packaged allograft implant of claim  9 , wherein the mesh lines have a length of 1.0 mm to 3.48 mm. 
     
     
         3 . The packaged allograft implant of claim  9 , wherein the mesh lines have a length of 3.48 mm. 
     
     
         4 . The packaged allograft implant of claim  9 , wherein the mesh lines have a spacing apart from one another of 1.0 mm to 1.5 mm. 
     
     
         5 . The packaged allograft implant of claim  9 , wherein the mesh lines have a spacing apart from one another of 1.5 mm. 
     
     
         6 - 8 . (canceled) 
     
     
         9 . A packaged allograft implant configured for implantation in a human recipient, the packaged allograft implant comprising:
 an acellular dermal matrix sheet having a top surface and a bottom surface in opposition to one another, a perimeter surrounding the top surface and the bottom surface, and a thickness extending between the top surface and the bottom surface; and   a mesh pattern extending across at least a portion of the top surface and the bottom surface of the acellular dermal matrix sheet, the mesh pattern providing through-holes extending between the top surface and the bottom surface of the acellular dermal matrix sheet, and the mesh pattern having a plurality of mesh lines extending in a first direction and a second direction, wherein the first direction and the second direction are orthogonal to one another so as to allow a given amount of stretch in each of the first direction and the second direction;   wherein the mesh pattern is a multiple quadrant pattern, with parallel mesh lines in opposing quadrants and perpendicular mesh lines in neighboring quadrants, and the multiple quadrant pattern contained in a circular shaped perimeter with the mesh lines.   
     
     
         10 . A packaged allograft implant configured for implantation in a human recipient, the packaged allograft implant comprising:
 an acellular dermal matrix sheet having a top surface and a bottom surface in opposition to one another, a perimeter surrounding the top surface and the bottom surface, and a thickness extending between the top surface and the bottom surface; and   a mesh pattern extending across at least a portion of the top surface and the bottom surface of the acellular dermal matrix sheet, the mesh pattern providing through-holes extending between the top surface and the bottom surface of the acellular dermal matrix sheet, and the mesh pattern having a plurality of mesh lines extending in a first direction and a second direction, wherein the first direction and the second direction are orthogonal to one another so as to allow a given amount of stretch in each of the first direction and the second direction;   wherein the mesh pattern is a row pattern formed by column of horizontal mesh lines followed by a column of vertical mesh lines, with the lines alternating for each column, with the mesh lines disposed on an acellular dermal matrix sheet forming an allograft for implantation in a human recipient.   
     
     
         11 . (canceled) 
     
     
         12 . A packaged allograft implant configured for implantation in a human recipient, the packaged allograft implant comprising:
 an acellular dermal matrix sheet having a top surface and a bottom surface in opposition to one another, a perimeter surrounding the top surface and the bottom surface, and a thickness extending between the top surface and the bottom surface; and   a mesh pattern extending across at least a portion of the top surface and the bottom surface of the acellular dermal matrix sheet, the mesh pattern providing through-holes extending between the top surface and the bottom surface of the acellular dermal matrix sheet, and the mesh pattern having a plurality of mesh lines extending in a first direction and a second direction, wherein the first direction and the second direction are orthogonal to one another so as to allow a given amount of stretch in each of the first direction and the second direction;   wherein the mesh pattern is an alternating semi-circle mesh pattern with arcuate mesh lines positioned in an alternating configuration with one another, with the mesh lines disposed on an acellular dermal matrix sheet forming an allograft for implantation in a human recipient.   
     
     
         13 - 19 . (canceled) 
     
     
         20 . The packaged allograft implant of  claim 10 , wherein the mesh lines have a length of 1.0 mm to 3.48 mm. 
     
     
         21 . The packaged allograft implant of  claim 10 , wherein the mesh lines have a length of 3.48 mm. 
     
     
         22 . The packaged allograft implant of  claim 10 , wherein the mesh lines have a spacing apart from one another of 1.0 mm to 1.5 mm. 
     
     
         23 . The packaged allograft implant of  claim 10 , wherein the mesh lines have a spacing apart from one another of 1.5 mm. 
     
     
         24 . The packaged allograft implant of  claim 12 , wherein the mesh lines have a length of 1.0 mm to 3.48 mm. 
     
     
         25 . The packaged allograft implant of  claim 12 , wherein the mesh lines have a length of 3.48 mm. 
     
     
         26 . The packaged allograft implant of  claim 12 , wherein the mesh lines have a spacing apart from one another of 1.0 mm to 1.5 mm. 
     
     
         27 . The packaged allograft implant of  claim 12 , wherein the mesh lines have a spacing apart from one another of 1.5 mm.