US2025326837A1PendingUtilityA1

Anti-tigit antibodies and methods of use

78
Assignee: GENENTECH INCPriority: Sep 25, 2015Filed: Jan 17, 2025Published: Oct 23, 2025
Est. expirySep 25, 2035(~9.2 yrs left)· nominal 20-yr term from priority
Inventors:Jane L. GroganRobert J. JohnstonYan WuWei-Ching LiangPatrick J. LupardusMahesh YadavDhaya SeshasayeeMeredith Hazen
Y02A50/30C07K 2317/90C07K 2317/70C07K 2317/34C07K 2317/33A61K 2039/505C07K 2317/55C07K 2317/24C07K 2317/94A61K 2039/507C07K 2317/75C07K 2317/76C07K 2317/92C07K 2317/567C07K 2317/56C07K 16/2878A61K 38/177C07K 16/2827A61K 45/06C07K 16/2818A61K 39/39558C07K 16/3061C07K 16/28A61P 43/00A61P 37/04A61P 37/02A61P 37/00A61P 35/02A61P 35/00A61P 31/00C07K 16/2803
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Claims

Abstract

The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.

Claims

exact text as granted — not AI-modified
1 . An antibody that specifically binds to human TIGIT, wherein the antibody binds to an epitope on human TIGIT comprising one or more of amino acid residues Ser78, Ser80, and Lys82 of human TIGIT. 
     
     
         2 - 182 . (canceled)

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