Initial total daily insulin setting for user onboarding

Abstract

Disclosed are techniques to establish initial settings for an automatic insulin delivery device. An adjusted total daily insulin (TDI) factor usable to calculate a TDI dosage may be determined. The adjusted TDI factor may be a TDI per unit of a physical characteristic of the user (e.g., weight) times a reduction factor. The adjusted TDI factor may be compared to a maximum algorithm delivery threshold. Based on the comparison result, the application or algorithm may set a TDI dosage and output a control signal. Blood glucose measurement values may be collected from a sensor over a period of time. A level of glycated hemoglobin of the blood may be determined based on the obtained blood glucose measurement values. In response to the level of glycated hemoglobin, the set TDI dosage may be modified. A subsequent control signal including the modified TDI dosage may be output to actuate delivery of insulin.

What is claimed is: 
     
         1 . A non-transitory computer readable medium embodied with programming code executable by a processor, and the processor when executing the programming code is operable to perform functions, including functions to:
 receive a weight of a user of an automatic therapeutic agent delivery device;   initialize one or more settings for the automatic therapeutic agent delivery device using the input weight;   receive user-provided information relating to consumption of a meal;   determine an appropriate level of a therapeutic agent to be administered to the user based on the user-provided information and the one or more settings; and   output a control signal including the determined level of the therapeutic agent instructing a controller of the therapeutic agent delivery device to actuate delivery of the therapeutic agent according to the determined level.   
     
     
         2 . The medium of  claim 1 , wherein the one or more settings comprise an initial dose setting for delivery of the therapeutic agent. 
     
     
         3 . The medium of  claim 1 , wherein the therapeutic agent comprises insulin and the control signal comprises an instruction to artificial pancreas logic. 
     
     
         4 . The medium of  claim 1 , wherein the one or more initial settings are determined based on a total daily insulin value for the user, and the settings are established based on a relationship between the user's weight and the total daily insulin value. 
     
     
         5 . The medium of  claim 4 , wherein the total daily insulin value is determined based on a total daily insulin per unit of the user's weight reduced by a reduction factor. 
     
     
         6 . The medium of  claim 1 , wherein the functions further comprise functions to:
 obtain glucose measurement values over a period of time;   evaluate the blood glucose measurement values with respect to one or more cost functions;   based on the evaluation, determine a reduction proportion to be applied to a total daily therapeutic agent amount per unit of the user's weight; and   apply the reduction proportion to the modified determined level of the therapeutic agent, wherein the reduction proportion reduces the total daily therapeutic agent amount.   
     
     
         7 . The medium of  claim 1 , wherein the one or more settings are initialized using only the input weight as a user-provided input. 
     
     
         8 . The non-transitory computer readable medium of  claim 1 , further embodied with programming code executable by the processor, and the processor when executing the programming code is further operable to perform functions, including functions to:
 in response to receipt of the request to establish initial settings for an automatic insulin delivery device, determine an availability of an insulin delivery history for the user; and   in response to the insulin delivery history for the user being unavailable, generate a prompt for the user to establish an initial setting for a total daily insulin dosage by inputting the user's weight.   
     
     
         9 . A computer-implemented method comprising:
 receiving a weight of a user of an automatic therapeutic agent delivery device;   initializing one or more settings for the automatic therapeutic agent delivery device using the input weight;   receiving user-provided information relating to consumption of a meal;   determining an appropriate level of the therapeutic agent to be administered to the user based on the user-provided information and the one or more settings; and   outputting a control signal including the determined level of the therapeutic agent instructing a controller of the therapeutic agent delivery device to actuate delivery of the therapeutic agent according to the determined level.   
     
     
         10 . The method of  claim 9 , wherein the one or more settings comprise an initial dose setting for delivery of the therapeutic agent. 
     
     
         11 . The method of  claim 9 , wherein the therapeutic agent comprises insulin and the control signal comprises an instruction to artificial pancreas logic. 
     
     
         12 . The method of  claim 9 , wherein the one or more initial settings are determined based on a total daily insulin value for the user, the settings are established based on a relationship between the user's weight and the total daily insulin value, and the total daily insulin value is determined based on a total daily insulin per unit of the user's weight reduced by a reduction factor. 
     
     
         13 . The method of  claim 9 , further comprising:
 obtaining glucose measurement values over a period of time;   evaluating the blood glucose measurement values with respect to one or more cost functions;   based on the evaluation, determining a reduction proportion to be applied to a total daily therapeutic agent amount per unit of the user's weight;   based on the obtained glucose measurement values, modifying the determined level of the therapeutic agent; and   applying the reduction proportion to the modified determined level of the therapeutic agent, wherein the reduction proportion reduces the total daily therapeutic agent amount.   
     
     
         14 . The method of  claim 9 , further comprising:
 in response to receipt of the request to establish initial settings for an automatic insulin delivery device, determining an availability of an insulin delivery history for the user; and   in response to the insulin delivery history for the user being unavailable, generating a prompt for the user to establish an initial setting for a total daily insulin dosage by inputting the user's weight.   
     
     
         15 . A device, comprising:
 a processor operable to execute programming code and applications;   a memory coupled to the processor and operable to store programming code, an artificial pancreas application and data;   a wireless communication device operable to wirelessly communicate with a paired device and communicatively coupled to the processor;   wherein the artificial pancreas application is executable by the processor, wherein the processor, when executing the artificial pancreas application, is operable to perform functions, including functions to:
 receive a weight of a user of an automatic therapeutic agent delivery device; 
 initialize one or more settings for the automatic therapeutic agent delivery device using the input weight; 
 receive user-provided information relating to consumption of a meal; 
 determine an appropriate level of the therapeutic agent to be administered to the user based on the user-provided information and the one or more settings; and 
 output a control signal including the determined level of the therapeutic agent instructing a controller of the therapeutic agent delivery device to actuate delivery of the therapeutic agent according to the determined level. 
   
     
     
         16 . The device of  claim 15 , wherein the one or more settings comprise an initial dose setting for delivery of the therapeutic agent. 
     
     
         17 . The device of  claim 15 , wherein the therapeutic agent is insulin. 
     
     
         18 . The device of  claim 15 , wherein the one or more initial settings are determined based on a total daily insulin value for the user, and the settings are established based on a relationship between the user's weight and the total daily insulin value, and the total daily insulin value is determined based on a total daily insulin per unit of the user's weight reduced by a reduction factor. 
     
     
         19 . The device of  claim 15 , further comprising:
 obtaining glucose measurement values over a period of time;   evaluating the blood glucose measurement values with respect to one or more cost functions;   based on the evaluation, determining a reduction proportion to be applied to a total daily therapeutic agent amount per unit of the user's weight;   based on the obtained glucose measurement values, modifying the determined level of the therapeutic agent; and   applying the reduction proportion to the modified determined level of the therapeutic agent, wherein the reduction proportion reduces the total daily therapeutic agent amount.   
     
     
         20 . The device of  claim 15 , further comprising:
 in response to receipt of the request to establish initial settings for an automatic insulin delivery device, determining an availability of an insulin delivery history for the user; and   in response to the insulin delivery history for the user being unavailable, generating a prompt for the user to establish an initial setting for a total daily insulin dosage by inputting the user's weight.