US2025127705A1PendingUtilityA1

Cosmetic compositions comprising a cyclodextrin having a particle size distribution

Assignee: ROQUETTE FRERESPriority: Dec 5, 2018Filed: Dec 24, 2024Published: Apr 24, 2025
Est. expiryDec 5, 2038(~12.4 yrs left)· nominal 20-yr term from priority
A61Q 19/004A61K 2800/412A61K 8/922A61K 8/73A61K 8/375A61K 8/345A61K 8/062A61Q 1/00A61Q 11/00A61Q 5/00A61Q 19/00A61K 8/34A61K 8/738A61K 8/0241
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Claims

Abstract

The present invention relates to cosmetic compositions comprising at least one cyclodextrin which is at least partially present in the form of solid particles dispersed in a physiologically acceptable medium, characterized in that the cyclodextrin particles have a volume average size d(4,3), measured by laser particle size analysis, of less than or equal to 20 μm, more preferentially less than or equal to 12 μm, and most preferentially less than or equal to 8 μm, and a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that: a. the diameter d(10) is less than or equal to 5.0 μm, preferentially less than or equal to 2.5 μm, b. and the diameter d(50) is less than or equal to 15.0 μm, preferentially less than or equal to 10.0 μm, c. and the diameter d(90) is less than or equal to 30.0 μm, preferentially less than or equal to 25.0 μm. The invention also relates to the use of such a cyclodextrin for improving the sensory profile of cosmetic compositions, in particular for conferring ease of spreading, and/or a soft, powdery, non-greasy feel, and for preventing the formation of pilling.

Claims

exact text as granted — not AI-modified
What is claimed: 
     
         1 . A cosmetic or dermatological composition comprising at least one cyclodextrin which is at least partially present in the form of solid particles dispersed in a physiologically acceptable medium, wherein the cyclodextrin particles have:
 a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 20 μm, and   a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that:   a. The diameter d(10) is less than or equal to 5.0 μm,   b. And the diameter d(50) is less than or equal to 15.0 μm,   c. And the diameter d(90) is less than or equal to 30.0 μm.   
     
     
         2 . The cosmetic or dermatological composition according to  claim 1 , wherein the solid cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, having a coefficient of variation of less than or equal to 100%. 
     
     
         3 . The cosmetic or dermatological composition according to  claim 1 , wherein at least 5% by weight of cyclodextrin, relative to the total weight of cyclodextrin present in the composition, is in the form of solid particles. 
     
     
         4 . The cosmetic or dermatological composition according to  claim 1 , wherein the content of cyclodextrin in the composition is 5% greater than the solubility thereof in the physiologically acceptable medium of said composition. 
     
     
         5 . The cosmetic or dermatological composition according to  claim 1 , wherein the cyclodextrin is a beta-cyclodextrin. 
     
     
         6 . The cosmetic or dermatological composition according to  claim 1 , wherein it forms a skincare product, a hair treatment, an oral-dental treatment, a make-up, or a hair-removing treatment. 
     
     
         7 . A method for improving the sensory properties of a cosmetic or a dermatological composition, wherein at least one cyclodextrin which is at least partially present in the form of solid particles dispersed in a physiologically acceptable medium is introduced in said cosmetic or dermatological composition, wherein the cyclodextrin particles have:
 a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 20 μm, more preferentially less than or equal to 12 μm, and   a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that:   a. The diameter d(10) is less than or equal to 5.0 μm,   b. And the diameter d(50) is less than or equal to 15.0 μm,   c. And the diameter d(90) is less than or equal to 30.0 μm.   
     
     
         8 . The method according to  claim 7 , wherein the solid cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, having a coefficient of variation of less than or equal to 100%. 
     
     
         9 . The method according to  claim 7 , wherein the cosmetic or dermatological compositions are selected from a skincare product, a hair treatment, an oral-dental treatment, make-up, or a hair-removing treatment. 
     
     
         10 . The method according to  claim 9 , wherein the cosmetic compositions are in the form of gels, emulsions, suspensions, lotions, serums, aerosols, mousses, pastes, powders or sticks, and preferentially of emulsions. 
     
     
         11 . A method for preparing a cosmetic or dermatological composition, comprising the following steps:
 a. providing a physiologically acceptable medium,   b. The dispersion, in said physiologically acceptable medium, of at least one cyclodextrin having a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 20 μm, and a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that:   a. The diameter d(10) is less than or equal to 5.0 μm,   b. And the diameter d(50) is less than or equal to 15.0 μm,   c. And the diameter d(90) is less than or equal to 30.0 μm.   
     
     
         12 . The method according to  claim 11 , wherein the content of cyclodextrin in the medium is 5% greater than the solubility thereof in said physiologically acceptable medium. 
     
     
         13 . The method according to  claim 7 , wherein the sensory properties are chosen from an ease spreading, and/or a soft, powdery, non-greasy feel, and/or the prevention of pilling. 
     
     
         14 . The cosmetic or dermatological composition according to  claim 1 , wherein the cyclodextrin particles have a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 12 μm. 
     
     
         15 . The cosmetic or dermatological composition according to  claim 1 , wherein the cyclodextrin particles have a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 8 μm. 
     
     
         16 . The cosmetic or dermatological composition according to  claim 1 , wherein the cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that:
 a. The diameter d(10) is less than or equal to 2.5 μm,   b. And the diameter d(50) is less than or equal to 10.0 μm,   c. And the diameter d(90) is less than or equal to 25.0 μm.   
     
     
         17 . The cosmetic or dermatological composition according to  claim 2 , wherein the solid cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, having a coefficient of variation of less than or equal to 90%. 
     
     
         18 . The cosmetic or dermatological composition according to  claim 2 , wherein the solid cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, having a coefficient of variation of less than or equal to 73%. 
     
     
         19 . The cosmetic or dermatological composition according to  claim 1 , wherein the cyclodextrin is a native beta-cyclodextrin. 
     
     
         20 . The method according to  claim 7 , wherein the cyclodextrin particles have a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 12 μm. 
     
     
         21 . The method according to  claim 7 , wherein the cyclodextrin particles have a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 8 μm. 
     
     
         22 . The method according to  claim 7 , wherein the cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that:
 a. The diameter d(10) is less than or equal to 2.5 μm,   b. And the diameter d(50) is less than or equal to 10.0 μm,   c. And the diameter d(90) is less than or equal to 25.0 μm.   
     
     
         23 . The method according to  claim 7 , wherein the solid cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, having a coefficient of variation of less than or equal to 90%. 
     
     
         24 . The method according to  claim 7 , wherein the solid cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, having a coefficient of variation of less than or equal to 73%. 
     
     
         25 . The method according to  claim 7 , wherein the cyclodextrin is a native beta-cyclodextrin. 
     
     
         26 . The method according to  claim 11 , wherein the cyclodextrin particles have a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 12 μm. 
     
     
         27 . The method according to  claim 11 , wherein the cyclodextrin particles have a volume average size d(4.3), measured by laser particle size analysis, of less than or equal to 8 μm. 
     
     
         28 . The method according  claim 11 , wherein the cyclodextrin particles have a size distribution by volume, measured by laser diffraction particle size analysis, of which the characteristic diameters d(10), d(50) and d(90) are such that:
 a. The diameter d(10) is less than or equal to 2.5 μm,   b. And the diameter d(50) is less than or equal to 10.0 μm,   c. And the diameter d(90) is less than or equal to 25.0 μm.

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