US2024156943A1PendingUtilityA1

Influenza vaccine

Assignee: DENKA COMPANY LTDPriority: Mar 30, 2021Filed: Mar 29, 2022Published: May 16, 2024
Est. expiryMar 30, 2041(~14.7 yrs left)· nominal 20-yr term from priority
A61K 39/00A61K 39/145A61K 9/0019A61P 31/16C12N 7/00A61K 2039/5252A61K 2039/54A61K 2039/55C12N 2760/16134C12N 2760/16163C12N 2760/16234C12N 2760/16263A61K 2039/545A61K 2039/575A61K 39/12
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Claims

Abstract

An influenza vaccine that has high immunogenicity in children and elderly people and has a higher efficacy than conventional split vaccines. An influenza vaccine composition to be administered to children and/or elderly people, including, as a virus antigen, inactivated whole particles subjected to inactivation treatment with beta-propiolactone.

Claims

exact text as granted — not AI-modified
1 . An influenza vaccine composition to be administered to children and/or elderly people, comprising, as a virus antigen, inactivated whole particles subjected to inactivation treatment with beta-propiolactone. 
     
     
         2 . The composition according to  claim 1 , wherein the virus antigen contains an influenza A virus strain including an A/H1N1 subtype and an A/H3N2 subtype, and an influenza B virus strain including a B/Victoria lineage and a B/Yamagata lineage. 
     
     
         3 . The composition according to  claim 1 , comprising no adjuvant. 
     
     
         4 . The composition according to  claim 1 , wherein the composition is subcutaneously administered. 
     
     
         5 . An immunization method comprising administering a composition containing, as a virus antigen, inactivated whole particles subjected to inactivation treatment with beta-propiolactone to children or elderly people. 
     
     
         6 . An influenza prevention method comprising administering a composition containing, as a virus antigen, inactivated whole particles subjected to inactivation treatment with beta-propiolactone to children or elderly people.

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