Contingent cardio-protection for epilepsy patents

Abstract

Disclosed are methods and systems for treating epilepsy by stimulating a main trunk of a vagus nerve, or a left vagus nerve, when the patient has had no seizure or a seizure that is not characterized by cardiac changes such as an increase in heart rate, and stimulating a cardiac branch of a vagus nerve, or a right vagus nerve, when the patient has had a seizure characterized by cardiac changes such as a heart rate increase.

What is claimed: 
     
         1 . A system for treating a medical condition in a patient, comprising:
 a sensor for sensing at least one body data stream;   a heart rate unit capable of determining a heart rate oscillation of the patient based on the at least one body data stream; and   a logic unit configured via one or more processors to compare a monitored value which is determined based on one or more data points relating to the heart rate oscillation to a threshold value, the logic unit further configured to determine a triggering event based on the comparison;   wherein the one or more processors are configured to initiate one or more actions to change the heart rate of the patient based on the determination of the triggering event.   
     
     
         2 . The system of  claim 1 , further comprising at least one electrode coupled to a vagus nerve of the patient and a programmable electrical signal generator. 
     
     
         3 . The system of  claim 2 , wherein the one or more processors are configured to increase a sympathetic tone to increase a heart rate of the patient. 
     
     
         4 . The system of  claim 2 , wherein the one or more processors are configured to decrease a parasympathetic tone to increase a heart rate of the patient. 
     
     
         5 . The system of  claim 2 , wherein the one or more processors are configured to decrease a sympathetic tone to decrease a heart rate of the patient. 
     
     
         6 . The system of  claim 2 , wherein the one or more processors are configured to increase a parasympathetic tone to decrease a heart rate of the patient. 
     
     
         7 . The system of  claim 1 , further comprising a seizure detection unit capable of analyzing the at least one body data stream to determine an epileptic seizure status. 
     
     
         8 . The system of  claim 7 , further comprising at least one electrode coupled to a vagus nerve of the patient and a programmable electrical signal generator;
 wherein the one or more processors are configured to apply an electrical signal to the vagus nerve of the patient based on a determination that a seizure is characterized by a decrease in a heart rate of the patient, wherein the electrical signal is applied to block action potential conduction on the vagus nerve.   
     
     
         9 . The system of  claim 1 , wherein the heart unit is configured to determine an inter-maxima interval and an inter-minima interval between a first oscillation and a second oscillation. 
     
     
         10 . The system of  claim 9 , wherein the logic unit is configured to compare the inter-maxima interval and the inter-minima interval to an interval threshold. 
     
     
         11 . The system of  claim 10 , wherein the one or more processors are further configured to initiate one or more actions based on the interval threshold being reached. 
     
     
         12 . A system for treating a medical condition in a patient, comprising:
 a sensor for sensing at least one body data stream;   at least one electrode coupled to a vagus nerve of the patient;   a programmable electrical signal generator;   a heart rate unit capable of determining a heart rate of the patient based on the at least one body data stream; and   a logic unit configured via one or more processors to compare a monitored value which is determined based on one or more data points relating to the heart rate to one or more threshold values, the logic unit further configured to determine a triggering event based on the comparison;   wherein the one or more processors are configured to initiate one or more actions to change the heart rate of the patient based on the determination of the triggering event.   
     
     
         13 . The system of  claim 12 , wherein the one or more processors are configured to increase a sympathetic tone or to decrease a sympathetic tone to increase the heart rate of the patient based on a first triggering event. 
     
     
         14 . The system of  claim 13 , wherein the one or more processors are configured to decrease a sympathetic tone to decrease the heart rate of the patient based on a second triggering event. 
     
     
         15 . The system of  claim 14 , wherein the one or more processors are configured to decrease the parasympathetic tone to increase the heart rate of the patient based on a third triggering event. 
     
     
         16 . The system of  claim 15 , wherein the one or more processors are configured to increase the parasympathetic tone to decrease the heart rate of the patient based on a fourth triggering event. 
     
     
         17 . The system of  claim 12 , wherein the one or more processors are configured to increase the sympathetic tone to increase the heart rate of the patient based on a second triggering event. 
     
     
         18 . The system of  claim 17 , wherein the one or more processors are configured to increase the sympathetic tone to increase the heart rate of the patient based on a third triggering event. 
     
     
         19 . The system of  claim 18 , wherein the one or more processors are configured to increase the sympathetic tone to increase the heart rate of the patient based on an nth triggering event. 
     
     
         20 . The system of  claim 12 , wherein the one or more processors are configured to decrease a sympathetic tone to decrease the heart rate of the patient based on a first triggering event.