US2024009100A1PendingUtilityA1

Hair care compositions comprising a 2-pyridinol-n-oxide material and an iron chelator

Assignee: PROCTER & GAMBLEPriority: Jun 30, 2017Filed: Sep 22, 2023Published: Jan 11, 2024
Est. expiryJun 30, 2037(~10.9 yrs left)· nominal 20-yr term from priority
A61K 8/4906A61K 8/44A61K 8/42A61K 8/55A61K 8/4926A61K 8/411A61K 8/463A61K 8/494A61K 8/8158A61Q 5/00A61K 8/41A61Q 5/006A61Q 5/02A61Q 5/12A61K 2800/51A61K 2800/5426
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Claims

Abstract

The present invention is directed to a hair care composition having an effective amount of a 2-pyridinol-N-oxide material and an effective amount of an iron chelator; wherein the combination of the iron chelator and the 2-pyridinol-N-oxide material provides high anti-fungal efficacy.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A hair care composition comprising:
 a) about 10% to about 20% of a detersive surfactant   b) about 0.1% to about 10% of 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt;   c) from about 0.3% to about 6% of desferrioxamine wherein the combination of 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt and desferrioxamine has a modified fractional inhibitor concentration of less than about 50 ppm;   d) from about 40% to about 95% aqueous carrier.   
     
     
         2 . The hair care composition of  claim 1  wherein the iron chelator has a log K 1  greater than about 16. 
     
     
         3 . The hair care composition of  claim 2 , wherein the iron chelator is at least one of diethylenetriaminepentakis (methylenephosphonic acid) and diethylenetriaminepentaacetic acid. 
     
     
         4 . The hair care composition of  claim 3 , wherein the total amount of diethylenetriaminepentakis (methylenephosphonic acid) and diethylenetriaminepentaacetic acid present in the composition is about 0.1% to about 15%. 
     
     
         5 . The hair care composition of  claim 1  wherein the 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt is present at about 0.3% to about 3%. 
     
     
         6 . The hair care composition of  claim 1  wherein the hair composition is a shampoo composition further comprising about 5% to about 45% of one or more detersive surfactants. 
     
     
         7 . The hair care composition of  claim 6 , wherein the detersive surfactant comprises an anionic surfactant selected from alkyl sulfates, alkyl ether sulfates, reaction products of fatty acids esterified with isethionic acid, and combinations thereof. 
     
     
         8 . The hair care composition of  claim 6 , wherein the detersive surfactant comprises an amphoteric surfactant selected from derivatives of aliphatic secondary and tertiary amines, wherein one of the aliphatic substituents contains about 8 to about 18 carbon atoms and one of the aliphatic substituents contains an anionic group selected from carboxy, sulfonate, sulfate, phosphate, and phosphonate. 
     
     
         9 . The hair care composition of  claim 6 , wherein the detersive surfactant comprises a zwitterionic surfactant selected from quaternary ammonium, phosphonium, and sulfonium materials, wherein one of the aliphatic substituents contains about 8 to about 18 carbon atoms and one of the aliphatic substituents contains an anionic carboxy, sulfonate, sulfate, phosphate or phosphonate group. 
     
     
         10 . The hair care composition of  claim 1 , wherein the hair composition is a rinse-off hair conditioner composition comprising about 50% to about 80% of an aqueous carrier and gel matrix, the gel matrix comprising:
 a) about 0.1% to about 20% of one or more high melting point fatty compound, by weight of the conditioner gel matrix;   b) about 0.1% to about 10% of a cationic surfactant system, by weight of the conditioner gel matrix; and   c) at least 20% of a second aqueous carrier, by weight of the conditioner gel matrix.   
     
     
         11 . The hair care composition of  claim 10 , wherein the cationic surfactant system comprises a cationic surfactant selected from mono-long alkyl quaternized ammonium salts, di-long alkyl quaternized ammonium salts, mono-long alkyl amidoamine salts, di-long alkyl quaternized ammonium salts, mono-long alkyl quaternized ammonium salts, and combinations thereof. 
     
     
         12 . The hair care composition of  claim 1 , wherein the hair composition is a leave-on treatment composition further comprising:
 a) about 0.1% to about 20% of one or more high melting point fatty compound, by weight of the conditioner gel matrix;   b) about 0.1% to about 10% of a cationic surfactant system, by weight of the conditioner gel matrix; and   c) at least 20% of a second aqueous carrier, by weight of the conditioner gel matrix.   
     
     
         13 . The hair care composition of  claim 1 , wherein the hair composition is a leave-on treatment composition further comprising 0.01-4% of a rheology modifier. 
     
     
         14 . The hair care composition of  claim 13  wherein the rheology modifier is a polymeric rheology modifier or polyacrylamide & C13-14 isoparaflin & laureth-7. 
     
     
         15 . The hair care composition of  claim 1  wherein the hair composition further comprises one or more additional anti-dandruff active agents selected from the group consisting of climbazole, ketoconazole, itraconazole, econazole, elubiol and combinations thereof.

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