Cannabinoid Lipid Premixture

Abstract

The invention relates to a powder premixture for oral administration of cannabinoids, comprising a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture; a lipid composition comprising one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and a sweetener powder composition comprising one or more sweeteners, wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4.

1 - 135 . (canceled) 
     
     
         136 . A powder premixture for oral administration of cannabinoids, comprising:
 a cannabinoid powder composition comprising one or more isolated cannabinoids in an amount of at least 2% by weight of the powder premixture;   a lipid composition comprising one or more triglycerides in an amount of at least 1.0% by weight of the powder premixture; and   a sweetener powder composition comprising one or more sweeteners,   wherein the weight ratio between the one or more triglycerides and the one or more sweeteners is in the range of 1:50 to 1:4.   
     
     
         137 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is selected from one or more C4 to C14 triglycerides. 
     
     
         138 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is selected from one or more C6 to C12 triglycerides. 
     
     
         139 . The powder premixture according to  claim 136 , wherein the one or more triglycerides comprises a partially hydrogenated vegetable oil or a fully hydrogenated vegetable oil. 
     
     
         140 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is selected from triglycerides being liquid at or above 0 Degree Celsius. 
     
     
         141 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is a blend of a number of triglycerides. 
     
     
         142 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is heated to a temperature above ambient temperature before being added in the premixture. 
     
     
         143 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is heated to a temperature of 50 to 80 Degree Celsius before being added in the premixture. 
     
     
         144 . The powder premixture according to  claim 136 , wherein the one or more triglycerides comprises caprylic acid in an amount of 50 to 80% by weight. 
     
     
         145 . The powder premixture according to  claim 136 , wherein the one or more sweeteners is present in an amount of at least 50% by weight of the powder premixture. 
     
     
         146 . The powder premixture according to  claim 136 , wherein the one or more sweeteners comprises one or more sugar alcohols selected from the group consisting of sorbitol, xylitol, maltitol, isomalt, mannitol, erythritol, lactitol, and combinations thereof. 
     
     
         147 . The powder premixture according to  claim 136 , wherein the weight ratio between the one or more triglycerides and the one or more isolated cannabinoids is in the range of 1:40 to 1:1. 
     
     
         148 . The powder premixture according to  claim 136 , wherein the one or more isolated cannabinoids is present in an amount of at least 5% by weight of the powder premixture. 
     
     
         149 . The powder premixture according to  claim 136 , wherein the one or more isolated cannabinoids is selected from the group consisting of cannabidiol (CBD), cannabidiolic acid (CBDA), cannabidivarin (CBDV), and combinations thereof. 
     
     
         150 . The powder premixture according to  claim 136 , wherein the one or more isolated cannabinoids is selected from the group consisting of tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), tetrahydrocannabivarin (THCV), and combinations thereof. 
     
     
         151 . The powder premixture according to  claim 136 , wherein the one or more isolated cannabinoids is present in a purity of at least 90% (w/w). 
     
     
         152 . The powder premixture according to  claim 136 , wherein the one or more isolated cannabinoids is dissolved in the one or more triglycerides before admixture with the sweetener powder composition. 
     
     
         153 . The powder premixture according to  claim 136 , wherein the one or more isolated cannabinoids is added in the sweetener powder composition before admixture with the one or more triglycerides. 
     
     
         154 . The powder premixture according to  claim 136 , wherein the one or more triglycerides is added in the sweetener powder composition before admixture with the one or more isolated cannabinoids. 
     
     
         155 . The powder premixture according to  claim 136 , wherein the premixture is a ready-to-use premixture. 
     
     
         156 . The powder premixture according to  claim 136 , wherein the premixture is to be applied in an amount of 10-99.9% by weight in combination with further ingredients. 
     
     
         157 . A solid dosage form for oral administration of cannabinoids comprising a premixture according to  claim 136 . 
     
     
         158 . The solid dosage form according to  claim 157 , wherein the premixture is present in an amount of 10-100% by weight of the solid dosage form. 
     
     
         159 . The solid dosage form according to  claim 157 , wherein the solid dosage form is selected from the group consisting of a tablet, a chewing gum, a lozenge, and a pouch.