Systems and methods for monitoring and treatment of an injury

Abstract

Provided herein are systems and methods for monitoring and treatment of an injury. The system includes a control device, an implantable device and/or a wearable device, the implantable device configured to be implanted into a body, the implantable device having a sensing device for sensing a condition of the injury and a treatment device configured to apply a treatment to the injury based on the sensed conditions of the injury. Signals of the sensed condition are sent to the control device, and the control device controls the treatment device of the implantable device to apply treatment for the injury. When a wearable device is included, the wearable device may be configured to sense another condition related to the injury and send signal indicative thereof to the control device.

1 . A system for treatment of an injury, the system comprising:
 an implantable device configured to be implanted into a body, the implantable device having a first sensing device and a treatment device, the first sensing device configured to sense a first condition of the injury and to generate a signal corresponding to the first sensed condition, the treatment device configured to selectively provide treatment to the injury;   a wearable device configured to be wearable on or adjacent to an external portion of the body, the wearable device having a second sensing device configured to sense a second condition of the body related to the injury; and   a control device connected to the implantable device and connected to the wearable device, the control device configured to receive a first signal from the implantable device and a second signal from the wearable device, and to control the implantable device to selectively cause the treatment device to apply the treatment based on the first signal and/or the second signal.   
     
     
         2 . The system according to  claim 1 , wherein the implantable device comprises a first implantable device and a second implantable device. 
     
     
         3 . The system according to  claim 2 , wherein the first implantable device comprises an ultrasound imaging device configured to generate a signal corresponding to the injury after the implantable device is implanted into the body, and the treatment device of the first implantable device comprises an ultrasound treatment device and/or an electrical stimulation treatment device configured to apply treatment to the injury. 
     
     
         4 . The system according to  claim 3 , wherein the ultrasound imaging device is configured to send the first signal to the control device, and the control device is configured to control the ultrasound treatment device and/or the electrical stimulation treatment device to selectively apply the treatment to the injury. 
     
     
         5 . The system according to  claim 2 , wherein the second implantable device comprises a plurality of sensor devices and a catheter device configured to selectively drain spinal fluid from the body. 
     
     
         6 . The system according to  claim 5 , wherein the plurality of sensor devices comprise a temperature sensor, a pressure sensor and a biomarker sensor configured to sense conditions including temperature, pressure and biomarker conditions, and the sensor devices are configured to generate signals indicative of the sensed conditions and to send the signals to the control device. 
     
     
         7 . The system according to  claim 6 , wherein the control device is configured to control the catheter device to selectively drain spinal fluid from the body based on the signals received from the temperature sensor, the pressure sensor and/or the biomarker sensor. 
     
     
         8 . The system according to  claim 2 , further comprising a third implantable device, the third implantable device comprising an epidural spinal stimulator device configured to selectively apply electrical stimulation to a spinal cord. 
     
     
         9 . The system of  claim 1 , wherein the wearable device comprises a first wearable device, a second wearable device and a third wearable device. 
     
     
         10 . The system of  claim 9 , wherein the first wearable device comprises a blood pressure sensor configured to measure a blood pressure, the second wearable device comprises a bladder sensor device configured to sense a volume of a bladder, and the third wearable device comprises an electromyograph (EMG) sensor configured to monitor motion of a limb. 
     
     
         11 . The system of  claim 10 , wherein the EMG sensor includes a plurality of accelerometers configured to sense a motion of a limb of the human and to generate a signal corresponding to the sensed motion, and to send the signal corresponding to the sensed motion to the control device. 
     
     
         12 . A system for monitoring and treatment of a spinal cord injury, comprising:
 a first implantable device configured to be implantable into a body adjacent the spinal cord injury, the first implantable device including an imaging device configured to create an image of the spinal cord, and including a treatment device configured to selectively treat the injury;   a second implantable device configured to be implantable into the body, the second implantable device comprising a catheter device configured to selectively drain spinal fluid from the body and a plurality of sensor devices configured to sense conditions of the body;   a wearable device configured to be wearable on or adjacent to an external portion of the body, the wearable device including a sensor configured to sense a condition related to the injury; and   a control device connected to the first implantable device, connected to the second implantable device, and connected to the wearable device, the control device configured to receive the image from the first implantable device, to receive a signal from each of the sensor devices of the second implantable device, and to receive a signal corresponding to the sensed condition from the wearable device, and configured to control the first implantable device to cause the treatment device to selectively apply the treatment based on the image of the spinal cord, and to control the second implantable device to selectively cause the catheter device to drain the spinal fluid based on the sensed conditions of the body.   
     
     
         13 . (canceled) 
     
     
         14 . The system of  claim 12 , wherein the imaging device is an ultrasound imaging device and the treatment device is an ultrasound treatment device and/or an electrical stimulation treatment device configured to apply treatment to the injury. 
     
     
         15 . The system of  claim 12 , wherein the plurality of sensor devices comprise a temperature sensor, a pressure sensor and a biomarker sensor configured to sense conditions including temperature, pressure and biomarker conditions, and the sensor devices are configured to generate signals indicative of the sensed conditions and to send the signals to the control device. 
     
     
         16 . The system of  claim 12 , wherein the wearable device comprises a first wearable device, a second wearable device and a third wearable device. 
     
     
         17 . The system of  claim 16 , wherein the first wearable device comprises a blood pressure sensor configured to measure a blood pressure, the second wearable device comprises a bladder sensor device configured to sense a volume of a bladder, and the third wearable device comprises an electromyograph (EMG) sensor configured to monitor motion of a limb. 
     
     
         18 . A method for monitoring and treating an injury, the method comprising:
 implanting a first implantable device into a body, the implantable device having a sensor and a treatment device, the sensor configured to sense a first condition of the injury and to generate a signal corresponding to the first sensed condition, the treatment device configured to selectively provide treatment to the injury;   attaching a first wearable device on an external portion of the body, the first wearable device having a first sensing device configured to sense a second condition of the body related to the injury;   
       receiving signals from the first implantable device and from the wearable device at a control device outside the body; and
 controlling the first implantable device with the control device based on the signals received from the implantable device and/or from the first wearable device to selectively cause the treatment device to apply the treatment. 
 
     
     
         19 . The method of  claim 18 , wherein the injury is a spinal cord injury, and the first sensing device is an ultrasound imaging device configured to generate an image of the injury. 
     
     
         20 . The method of  claim 19 , wherein the treatment device of the first implantable device comprises an ultrasound treatment device and/or an electrical stimulation treatment device configured to apply treatment to the injury. 
     
     
         21 . The method of  claim 19 , further comprising:
 implanting a second implantable device into the body, the second implantable device comprising a plurality of sensor devices and a catheter device configured to selectively drain spinal fluid from the body;   receiving signals at the control device from the plurality of sensor devices; and   controlling the catheter device with the control device to selectively drain spinal fluid from the body based on the signals from the plurality of sensor devices.   
     
     
         22 . The method of  claim 21 , further comprising:
 attaching a second wearable device on an external portion of the body, the second wearable device having a second sensing device configured to sense a second condition of the body related to the injury;   attaching a third wearable device on an external portion of the body, the wearable device having a third sensing device configured to sense a second condition of the body related to the injury; and   receiving signals from the second wearable device and from the third wearable device at the control device.   
     
     
         23 - 30 . (canceled)