US2023398117A1PendingUtilityA1

3-hydroxy-N-(3-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)pyrrolidine-1-carboxamide Derivatives

Assignee: NOVARTIS AGPriority: Mar 26, 2018Filed: Dec 1, 2022Published: Dec 14, 2023
Est. expiryMar 26, 2038(~11.7 yrs left)· nominal 20-yr term from priority
A61K 31/519A61P 35/00C07D 487/04C07D 519/00
70
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Claims

Abstract

The invention relates to compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined in the specification; to intermediates in the preparation of the compounds, to pharmaceutical compositions comprising the compounds and to use of the compounds in the treatment of disease.

Claims

exact text as granted — not AI-modified
1 - 14 . (canceled) 
     
     
         15 . A compound of Formula (XXIa): 
       
         
           
           
               
               
           
         
       
       or a salt thereof,
 wherein: 
 R 6  is selected from H and F; and 
 R 7  is selected from H, F, Cl, —CH 3 , —OCH 3 , and —OCH 2 CH 3 . 
 
     
     
         16 . The compound of claim  1 , or a salt thereof, wherein R 6  is F. 
     
     
         17 . The compound of claim  1 , or a salt thereof, wherein R 7  is selected from F, Cl, —CH 3 , —OCH 3 , and —OCH 2 CH 3 . 
     
     
         18 . The compound of claim  1 , or a salt thereof, which is: 
       
         
           
           
               
               
           
         
       
       or a salt thereof.

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