US2023383331A1PendingUtilityA1

Methods and materials for assessing and treating arthritis

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Assignee: MAYO FOUND MEDICAL EDUCATION & RESPriority: Feb 3, 2015Filed: Mar 15, 2023Published: Nov 30, 2023
Est. expiryFeb 3, 2035(~8.5 yrs left)· nominal 20-yr term from priority
Inventors:Veena Taneja
C12Q 1/04A61K 35/66C12Q 1/689G01N 33/6806A61P 19/02A61K 35/741A61P 37/00G01N 2800/102
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Claims

Abstract

This document provides methods and materials involved in assessing mammals (e.g., humans) for arthritis. For example, methods and materials for assessing a mammal's gut microbial diversity to identify the mammal as having arthritis (e.g., rheumatoid arthritis) are provided. This document also provides methods and materials involved in treating arthritis.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method for treating arthritis, wherein said method comprises:
 (a) identifying a mammal as having arthritis,   (b) administering an antibiotic to said mammal to reduce the number of microbial organisms within the gut of said mammal, and   (c) administering a formulation comprising live microbial organisms, wherein said formulation lacks species from the  Eggerthella, Collinsella , and  Pseudomonas  genera.   
     
     
         2 . The method of  claim 1 , wherein said step (c) is performed between 2 days and 5 days after said step (b).

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