US2023346894A1PendingUtilityA1

Formulation with cannabinoids

Assignee: PAW POWER INCPriority: Sep 4, 2018Filed: Oct 21, 2022Published: Nov 2, 2023
Est. expirySep 4, 2038(~12.1 yrs left)· nominal 20-yr term from priority
Inventors:Anja Skodda
A61K 31/658A61K 38/39A23L 33/105A23L 33/125A23L 33/15A23L 33/17A61K 9/0056A61K 31/352A61K 31/355A61K 31/375A61K 31/593A61K 31/7008A61K 31/728A23V 2002/00A61K 9/19A61K 9/0095A61K 9/0053A23L 33/10A23L 33/18
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Claims

Abstract

A food supplement comprising a therapeutically effective amount of a composition is described. The composition includes hydrolyzed collagen, hyaluronic acid, ascorbic acid, and glucosamine hydrochloride. The composition may also include a cannabinoid or prodrug, vitamin C, vitamin D, and/or vitamin E. The therapeutically effective amount of the composition is effective in alleviating at least one symptom of a degenerative joint disease in a human or may be used for the prophylaxis of the degenerative joint disease in the human. The at least one symptom of the degenerative joint disease in the human includes joint pain and mobility pain.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method to create a food supplement effective at alleviating at least one symptom of a degenerative joint disease in a human or for the prophylaxis of the degenerative joint disease in the human, the method comprising:
 engaging in enzymatic hydrolysis of a collagen with a protease to create a hydrolyzed collagen; and   adding a formulation to the hydrolyzed collagen to create the food supplement.   
     
     
         2 . The method of  claim 1 , wherein the formulation comprises:
 hyaluronic acid;   glucosamine hydrochloride; and   a vitamin composition, wherein the vitamin composition is selected from the group consisting of: vitamin C, vitamin D, and vitamin E.   
     
     
         3 . The method of  claim 2 , wherein the formulation further comprises a cannabinoid or prodrug thereof. 
     
     
         4 . The method of  claim 3 , wherein the enzymatic hydrolysis of the collagen with the protease to create the hydrolyzed collagen comprises:
 washing and drying mammal shavings;   soaking the mammal shavings in an amount of water at a first temperature for a first time period to create a solution; and   adjusting a pH of the solution.   
     
     
         5 . The method of  claim 4 , wherein the mammal shavings comprise pigskin shavings. 
     
     
         6 . The method of  claim 4 ,
 wherein the amount of the water comprises nine-fold water (w/v),   wherein the first temperature comprise approximately 60° C., and   wherein the first time period comprises approximately 30 minutes.   
     
     
         7 . The method of  claim 4 , wherein adjusting the pH of the solution occurs with 1 M hydrochloric acid (HCl) or 1 M sodium hydroxide (NaOH). 
     
     
         8 . The method of  claim 4 , wherein the enzymatic hydrolysis of the collagen with the protease to create the hydrolyzed collagen further comprises:
 adding an amount of the protease to the solution;   hydrolyzing the solution at a second temperature and for a second time period;   terminating the hydrolysis;   cooling the solution;   adjusting the pH of the solution;   filtering the solution;   dialyzing the filtrate at a third temperature for a third time period; and   obtaining the hydrolyzed collagen.   
     
     
         9 . The method of  claim 8 , wherein the amount of the protease comprises a range between approximately 700 U/g of the mammal shavings to approximately 800 U/g of the mammal shavings. 
     
     
         10 . The method of  claim 8 ,
 wherein the termination of the hydrolysis occurs by inactivating the protease at a fourth temperature for a fourth time period,   wherein the fourth temperature is approximately 100° C., and   wherein the fourth time period is approximately 5 minutes.   
     
     
         11 . The method of  claim 8 , wherein adjusting the pH of the solution occurs to a pH of 7. 
     
     
         12 . The method of  claim 8 ,
 wherein the second temperature is an optimal temperature for the protease,   wherein the second time period is approximately 4 hours,   wherein the third temperature is room temperature, and   wherein the third time period is approximately 48 hours.   
     
     
         13 . The method of  claim 8 , wherein the hydrolyzed collagen is obtained via freeze-drying.

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