Methods and Compositions for Treating a Disease Condition in a Subject

Abstract

Methods for treating a disease condition in a subject are provided. The subject methods are characterizing by enhancing at least one symptom of the disease condition in a manner effective to cause the subject to mount a compensatory response effective to treat the disease condition. Also provided are compositions, kits and systems for practicing the subject methods.

What is claimed is: 
     
         1 . A method of treating a subject for a disease condition, said method comprising:
 enhancing at least one symptom of said disease condition in a manner effective to cause said subject to mount a compensatory response effective to treat said disease condition.   
     
     
         2 . The method according to  claim 1 , wherein said enhancing comprises applying a stimulus to said subject. 
     
     
         3 . The method according to  claim 2 , wherein said stimulus is a pharmacological agent. 
     
     
         4 . The method according to  claim 2 , wherein said stimulus is an electrical stimulus. 
     
     
         5 . The method according to  claim 1 , wherein said disease condition is a manifestation of an irregularity in a homeostatic pathway. 
     
     
         6 . The method according to  claim 5 , wherein said disease condition is manifested by chronic sympathetic bias. 
     
     
         7 . The method according to  claim 6 , wherein said disease condition is a cardiovascular disease. 
     
     
         8 . The method according to  claim 7 , wherein said cardiovascular disease is hypertension. 
     
     
         9 . The method according to  claim 7 , wherein said stimulus is a pharmacological agent. 
     
     
         10 . The method according to  claim 9 , wherein said pharmacological agent is an adrenergic agonist. 
     
     
         11 . The method according to  claim 1 , wherein said disease condition is a neurological condition. 
     
     
         12 . The method according to  claim 11 , wherein said neurological condition is depression. 
     
     
         13 . The method according to  claim 12 , wherein said agent is a serotonin antagonist. 
     
     
         14 . The method according to  claim 1 , wherein said disease condition is an immune condition. 
     
     
         15 . The method according to  claim 14 , wherein said immune condition is asthma. 
     
     
         16 . The method according to  claim 15 , wherein said agent is a proinflammatory agent. 
     
     
         17 . The method according to  claim 1 , wherein said disease condition is an endocrine system condition. 
     
     
         18 . The method according to  claim 17 , wherein said disease condition is diabetes. 
     
     
         19 . The method according to  claim 18 , wherein said agent is an insulin blocker. 
     
     
         20 . The method according to  claim 1 , wherein said administering is of limited temporal duration. 
     
     
         21 . The method according to  claim 1 , wherein said method comprises monitoring said subject. 
     
     
         22 . The method according to  claim 21 , wherein said method comprises applying a first stimulus to said subject and monitoring said subject for a response thereto; and applying a second stimulus to said subject, wherein said second stimulus is determined based on said monitored response to said first stimulus. 
     
     
         23 . The method according to  claim 22 , wherein said first stimulus is a pharmacological agent. 
     
     
         24 . The method according to  claim 22 , wherein said first stimulus is electrical energy. 
     
     
         25 . An algorithm recorded on a computer-readable medium for administering a stimulus to said subject in accordance with method of  claim 2 . 
     
     
         26 . A system comprising:
 an algorithm recorded on a computer-readable medium for administering a stimulus to a subject according to a method of  claim 2 ; and a stimulus producing component.   
     
     
         27 . The system according to  claim 26 , wherein said stimulus producing component is a pharmacological agent delivery device. 
     
     
         28 . The system according to  claim 27 , wherein said stimulus producing component is an electrical energy applying device. 
     
     
         29 . A kit comprising:
 a stimulus producing component; and instructions for a stimulus to a subject according to the method of  claim 2 .   
     
     
         30 . The kit according to  claim 29 , wherein said stimulus producing component is a pharmacological agent delivery device. 
     
     
         31 . The kit according to  claim 29 , wherein said stimulus producing component is an electrical energy applying device.