Composition for promoting absorption of phytochemicals

Abstract

Disclosed is a composition for promoting absorption of a poorly water-soluble phytochemical which can significantly improve the intake of a phytochemical into a body, especially a migration speed and/or a migration amount of the phytochemical into a blood. A polysaccharide-containing lactic acid bacterial product, which is produced by Lactobacillus delbrueckii ssp. bulgaricus OLL1251, can significantly enhance the intake of a phytochemical into a body, especially a migration speed and/or a migration amount of the phytochemical into a blood. Thus, the composition for promoting absorption of a phytochemical according to the present invention includes, as an active ingredient, the polysaccharide-containing lactic acid bacterial product. Furthermore, the composition for promoting absorption of a phytochemical is useful as a food additive composition. In addition, a food, or a beverage, or a food or beverage composition to which the composition for promoting absorption of a phytochemical is added can obtain an effect of promoting absorption of phytochemical.

What is claimed is: 
     
         1 . A method for preparing a composition, the method comprising:
 fermenting a raw material with  Lactobacillus delbrueckii  ssp.  bulgaricus  OLL1251 with an accession number NITE BP-02703.   
     
     
         2 . The method according to  claim 1 , wherein the composition is fermented milk. 
     
     
         3 . The method according to  claim 2 , wherein the fermented milk is produced by a combination of  Lactobacillus delbrueckii  ssp.  bulgaricus  OLL1251 with an accession number NITE BP-02703 and  Streptococcus thermophilus  OLS3290 with an accession number FERM BP-19638. 
     
     
         4 . A method for preparing a composition comprising a polysaccharide-containing lactic acid bacterial product, the method comprising:
 fermenting a raw material with  Lactobacillus delbrueckii  ssp.  bulgaricus  OLL1251 with an accession number NITE BP-02703.   
     
     
         5 . The method according to  claim 4 , wherein the composition is fermented milk. 
     
     
         6 . The method according to  claim 5 , wherein the fermented milk is produced by a combination of  Lactobacillus delbrueckii  ssp.  bulgaricus  OLL1251 with an accession number NITE BP-02703 and  Streptococcus thermophilus  OLS3290 with an accession number FERM BP-19638. 
     
     
         7 . A composition, comprising:
 a poorly water-soluble phytochemical, and   a polysaccharide-containing lactic acid bacterial product produced by at least a  Lactobacillus delbrueckii  ssp.  bulgaricus  OLL1251 with an accession number NITE BP-02703.   
     
     
         8 . The composition according to  claim 7 , wherein the lactic acid bacterial product is a product produced by a combination of  Lactobacillus delbrueckii  ssp.  bulgaricus  OLL1251 with an accession number NITE BP-02703 and  Streptococcus thermophilus  OLS3290 with an accession number FERM BP-19638. 
     
     
         9 . The composition according to  claim 7 , wherein the poorly water-soluble phytochemical has the dissolution rate in water of 88% or less. 
     
     
         10 . The composition according to  claim 7 , wherein the poorly water-soluble phytochemical has the dissolution rate in water of 50% or less. 
     
     
         11 . The composition according to  claim 7 , wherein the poorly water-soluble phytochemical is selected from the group consisting of a polyphenol, an organic sulfur compound, and a terpenoid. 
     
     
         12 . The composition according to  claim 11 , wherein the poorly water-soluble phytochemical is a flavonoid. 
     
     
         13 . The composition according to  claim 12 , wherein the flavonoid is selected from the group consisting of flavone, isoflavone, flavonol, flavanone, flavan-3-ol, anthocyanin, and an analogue thereof. 
     
     
         14 . The composition according to  claim 13 , wherein the poorly water-soluble phytochemical is selected from the group consisting of flavone, isoflavone, flavonol, flavanone, flavan-3-ol, and an analogue thereof. 
     
     
         15 . The composition according to  claim 11 , wherein the poorly water-soluble phytochemical is tetraterpene or an analogue thereof. 
     
     
         16 . The composition according to  claim 7 , wherein the poorly water-soluble phytochemical is selected from the group consisting of quercetin, genistein, epicatechin, luteolin, naringenin, hesperidin, β-carotene, α-carotene, β-cryptoxanthin, capsanthin, lutein, lycopene, and an analogue thereof. 
     
     
         17 . The composition according to  claim 7 , wherein the composition is fermented milk. 
     
     
         18 . A food additive comprising the composition according to  claim 7 . 
     
     
         19 . A food, or a beverage, or a food or beverage composition comprising the composition according  claim 7 .