Screw control medical fluid flow manifolds

Abstract

Fluid flow manifold assemblies for use in fluid flow sets are provided. The fluid flow manifold assembly includes a body having a main fluid channel, an inlet connector, an outlet connector and a drug port. A flow control assembly is disposed opposite the main fluid channel from the drug port. The flow control assembly includes a plunger, a seal member and a knob, wherein the plunger is disposed within the main fluid flow channel in a full open flow position and is configured to extend through the main fluid channel and be sealingly received by the drug port in a closed position, wherein the plunger position is based on rotation of the knob. Fluid flow sets with fluid flow manifold assemblies are also provided.

1 . A fluid flow manifold assembly, comprising:
 a body having a main fluid channel;   an inlet connector coupled to an end of the main fluid channel;   an outlet connector coupled to an opposing end of the main fluid channel;   a drug port fluidly coupled to the main fluid channel; and   a flow control assembly coupled to the main fluid channel directly opposing the drug port, the flow control assembly comprising: 
 a plunger; 
 a seal member; and 
 a knob, 
   wherein the plunger is disposed within the main fluid flow channel in a full open flow position and is configured to extend through the main fluid channel and be sealingly received by the drug port in a closed position, wherein the plunger position is based on rotation of the knob.   
     
     
         2 . The fluid flow manifold assembly of  claim 1 , wherein the drug port is disposed orthogonally to the main fluid channel and the flow control assembly is disposed axially to the drug port. 
     
     
         3 . The fluid flow manifold assembly of  claim 1 , wherein the inlet connector is a female Luer connector. 
     
     
         4 . The fluid flow manifold assembly of  claim 1 , wherein the outlet connector is a male Luer connector. 
     
     
         5 . The fluid flow manifold assembly of  claim 1 , further comprising a port connector coupled to the drug port. 
     
     
         6 . The fluid flow manifold assembly of  claim 5 , wherein the port connector is a female Luer connector. 
     
     
         7 . The fluid flow manifold assembly of  claim 1 , the body further comprising a reinforcing plate disposed along a length of the body and extending orthogonally outward from the main fluid channel, the reinforcing plate having a surface for gripping the fluid flow manifold assembly. 
     
     
         8 . The fluid flow manifold assembly of  claim 7 , further comprising a cavity disposed in the reinforcing plate, wherein the knob and the seal member are disposed within the cavity and external to the main fluid channel. 
     
     
         9 . The fluid flow manifold assembly of  claim 8 , wherein the cavity has a stop surface configured to prevent the knob from being fully unscrewed off of the plunger. 
     
     
         10 . The fluid flow manifold assembly of  claim 7 , further comprising an indicator element disposed on the reinforcing plate. 
     
     
         11 . The fluid flow manifold assembly of  claim 10 , wherein the indicator element is one of printed on the reinforcing plate, etched onto the reinforcing plate and formed by a material of the reinforcing plate. 
     
     
         12 . The fluid flow manifold assembly of  claim 1 , wherein the seal member is disposed outside of the main fluid channel and the plunger is slidably moveable through the seal member. 
     
     
         13 . The fluid flow manifold assembly of  claim 1 , wherein the plunger is disposed within the main fluid channel in all positions between the full open flow position and the closed position. 
     
     
         14 . The fluid flow manifold assembly of  claim 13 , wherein the plunger is configured to allow fluid flow through the main fluid channel past the plunger with no dead space in all plunger positions between the full open flow position and the closed position. 
     
     
         15 . A fluid flow set, comprising:
 a fluid inlet tube;   a fluid outlet tube;   a drug delivery tube; and   a fluid flow manifold assembly, the fluid flow manifold assembly comprising: 
 a body having a main fluid channel; 
 an inlet connector coupled to an end of the main fluid channel; 
 an outlet connector coupled to an opposing end of the main fluid channel; 
 a drug port disposed orthogonally to the main fluid channel and fluidly coupled to the main fluid channel; and 
 a flow control assembly coupled to the main fluid channel and disposed axially opposing the drug port, the flow control assembly comprising: 
 a plunger; 
 a seal member disposed external to the main fluid channel; and 
 a knob disposed external to the main fluid channel, 
 
   wherein the plunger is disposed within the main fluid flow channel in a full open flow position and is configured to extend through the main fluid channel and be sealingly received by the drug port in a closed position, wherein the plunger position is based on rotation of the knob.   
     
     
         16 . The fluid flow set of  claim 15 , the body further comprising a reinforcing plate disposed along a length of the body and extending orthogonally outward from the main fluid channel, the reinforcing plate having a surface for gripping the fluid flow manifold assembly. 
     
     
         17 . The fluid flow set of  claim 16 , further comprising a cavity disposed in the reinforcement plate, the cavity having a stop surface configured to prevent the knob from being loosened past a defined point. 
     
     
         18 . The fluid flow set of  claim 15 , wherein the fluid flow manifold assembly comprises three drug ports and opposing flow control assemblies, each drug port coupled to a separate port connector and each separate port connector coupled to a separate drug delivery tube. 
     
     
         19 . The fluid flow set of  claim 15 , wherein the seal member is disposed outside of the main fluid channel and the plunger is slidably moveable through the seal member, and wherein the plunger is disposed within the main fluid channel in all positions between the full open flow position and the closed position. 
     
     
         20 . The fluid flow set of  claim 19 , wherein the plunger is configured to allow fluid flow through the main fluid channel past the plunger with no dead space in all plunger positions between the full open flow position and the closed position.