US2023048872A1PendingUtilityA1

Compositions and methods for diagnosing or treating neutrophil-mediated inflammatory disease

Assignee: UNIV ILLINOISPriority: Jun 28, 2013Filed: May 16, 2022Published: Feb 16, 2023
Est. expiryJun 28, 2033(~6.9 yrs left)· nominal 20-yr term from priority
A61K 31/05G01N 2800/22A61K 9/5169A61K 31/573G01N 33/5005A61K 9/0019A61K 9/1658
75
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Claims

Abstract

Disclosed are nanoparticle compositions comprising nanoparticles prepared from denatured, cross-linked albumin and a therapeutic agent for treating a neutrophil-mediated inflammation, and methods of treating neutrophil-mediated inflammation using the compositions.

Claims

exact text as granted — not AI-modified
1 . A composition comprising nanoparticles, the nanoparticles comprising denatured, cross-linked albumin and an agent selected from a therapeutic agent and a detectable moiety, the nanoparticles being capable of selectively binding to and being internalized by activated neutrophils.

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