Psilocybin compositions

Abstract

Methods and compositions are disclosed for enhancing neurogenesis, resolving neuropathy and improving neurological health and functioning using fungal extracts and their active ingredients, including species of mushrooms and mycelia containing psilocybin and psilocin, combined with erinacines and hericenones or fungal extracts containing those active ingredients, with the addition of nicotinic acid. The compositions may optionally be combined with nervine plants.

What is claimed: 
     
         1 . A method for improving neurological health of an animal comprising:
 administering a therapeutically effective amount of a composition to an animal, wherein
 the composition comprises: 
 one or more of psilocybin, psilocin, baeocystin, norbaeocystin, salts thereof, or combinations thereof; 
 one or more of erinacines, hericenones or combinations thereof; and 
 niacin. 
   
     
     
         2 . The method of  claim 1 , wherein the animal is a human. 
     
     
         3 . The method of  claim 1 , wherein the administering results in one or more of improved memory and cognition, improved motor skills and coordination, improved ability to solve complex computer coding challenges, improved hearing, improved vision, improved sensory function, improved learning, promotion of neurogenesis, or combinations thereof. 
     
     
         4 . The method of  claim 1 , wherein the composition further comprises one or more of extracts of  Bacopa monnieri, Centella asiatica, Gingko biloba, Zingiber officinale, Ocimum sanctum, Polygonum cuspid atum, Origanum vulgare, Origanum onites, Rosmarinus officinalis, Rosmarinus eriocalyx, Curcuma longa, Camellia sinensis, Lavandula  species,  Scutellaria lateriflora, Avena sativa  and  Avena byzantine, Salvia divinorum, Banisteriopsis caapi, Psychotria  species,  Tabemanthe iboga, Voacanga africana, Tabemaemontana undulate, Ipomoea tricolor, Argyreia nervosa, Cannabis sativa, Cannabis indica, Cannabis ruderalis,  or combinations thereof. 
     
     
         5 . The method of  claim 1 , wherein the composition further comprises one or more of: mycelia, fruitbodies, mycelial extracts, or fruitbody extracts of fungi selected from  Antrodia, Beauveria, Copelandia, Cordyceps, Ganoderma, Grifola, Hericium, Inonotus, Isaria, Panaeolus, Phellinus,  or combinations thereof. 
     
     
         6 . A method for improving neurological health comprising: administering a daily dose of a composition for at least one month to a patient, wherein the composition comprises: one or more of about 0.1 to 10 mg of psilocybin, psilocin, baeocystin, norbaeocystin, or salts thereof, one or more of about 0.1 to 1 gram of psilocybin mushrooms, or combinations thereof; about 0.1 to 200 mg of one or more of erinacines, hericenones, or combinations thereof; and about 1 to 200 mg of niacin. 
     
     
         7 . The method of  claim 6 , wherein the composition comprises about 0.6 to 10 mg of one or more of psilocybin, psilocin, baeocystin, norbaeocystin, salts thereof, or combinations thereof, about 20 to 200 mg of one or more of erinacines, hericenones, or combinations thereof, and about 50 to 200 mg of niacin. 
     
     
         8 . The method of  claim 6 , wherein the composition comprises about 0.9 to 10 mg of one or more of psilocybin, psilocin, baeocystin, norbaeocystin, salts thereof, or combinations thereof, about 50 to 200 mg of one or more of erinacines, hericenones, or combinations thereof, and about 50 to 200 mg of niacin. 
     
     
         9 . The method of  claim 6 , wherein the composition additionally comprises one or more of extracts of  Bacopa monnieri, Centella asiatica, Gingko biloba, Zingiber officinale, Ocimum sanctum, Polygonum cuspid atum, Origanum vulgare, Origanum onites, Rosmarinus officinalis, Rosmarinus eriocalyx, Curcuma longa, Camellia sinensis, Lavandula  species,  Scutellaria lateriflora, Avena sativa  and  Avena byzantine, Salvia divinorum, Banisteriopsis caapi, Psychotria  species,  Tabemanthe iboga, Voacanga africana, Tabemaemontana undulate, Ipomoea tricolor, Argyreia nervosa, Cannabis sativa, Cannabis indica, Cannabis ruderalis,  or combinations thereof. 
     
     
         10 . A method for improving neurological health of an animal comprising:
 administering a therapeutically effective amount of a composition to an animal, wherein the composition comprises:
 one or more of erinacines, hericenones, or combinations thereof; 
 niacin; and 
 one or more of N,N-dimethyltryptamine, 5-hydroxytryptamine, 5-hydroxytryptophan, 4-acetoxy-N,N-dimethyltryptamine, 4-acetoxy-N-methyl-N-ethyltryptamine, 4-acetoxy-N,N-diethyltryptamine, 4-acetoxy-N-methyl-Npropyltryptamine, 4-acetoxy-N-methyl-N-isopropyltryptamine, 4-acetoxy-N,N-dipropyltryptamine, 4-acetoxy-N,N-diisopropyl tryptamine, 4-hydroxy-N-methyl-N-ethyltryptamine, 4-hydroxy-N-methyl-N-propyltryptamine, 4-hydroxy-N-methyl-N-isopropyltryptamine, 4-hydroxy-N,N-diisopropyltryptamine, 4-hydroxy-N,N-diisopropyltryptamine, 4-hydroxy-N-methyl-N-propyltryptamine, 4-hydroxy-N,N-diethyltryptamine, 4-hydroxy-N,N-diallyltryptamine, N-methyl-N-ethyltryptamine, N, N-diethyltryptamine, N,N-dipropyltriptamine, N,N-diisopropyltryptamine, N-methyl-N-propyltryptamine, N-methyl-N-isopropyltryptamine, a-methyltryptamine, N-ethyl-N-isopropyltryptamine, N-methyl-N-butyltryptamine, N,N-dimethyl-5-hydroxytryptamine, 5-methoxy-a-methyltryptamine, 5-methoxy-N,N-dimethyltryptamine, 5-methoxy-N,N-diethyltryptamine, 5-methoxy-N,N-dipropyltryptamine, 5-methoxy-N,N -diisopropyltryptamine, 5-methoxy-N-ethyl-N-isopropyltryptamine, 2, α-dimethyltryptamine, α,N-dimethyltryptamine, α-ethyltryptamine, 2-methyl-N,N-dimethyltryptamine, 2-methyl-N,N-diethyltryptamine, 1-methylpsilocin, ibogaine, 4-hydroxindole-3-acetylaldehyde, 4-hydroxtryptophol, 4-hydroxindole-3-acetic acid, salts thereof, or combinations thereof. 
   
     
     
         11 . The method of  claim 10 , wherein the animal is a human. 
     
     
         12 . The method of  claim 10 , wherein the administering results in one or more of improved memory and cognition, improved motor skills and coordination, improved ability to solve complex computer coding challenges, improved hearing, improved vision, improved sensory function, improved learning, promotion of neurogenesis, or combinations thereof.