US2023013313A1PendingUtilityA1

Atlas registration for resting state network mapping in patients with brain tumors

Assignee: WASHINGTON UNIVERSITY ST LOUISPriority: May 30, 2019Filed: Sep 9, 2022Published: Jan 19, 2023
Est. expiryMay 30, 2039(~12.8 yrs left)· nominal 20-yr term from priority
A61B 5/055A61B 5/0263G06T 7/0014G06T 2207/30016G01R 33/4806G06T 2207/30096G06T 2207/20128A61B 5/0042G06T 2207/10088G06T 7/0012G06T 7/11A61B 2576/026G06T 7/149G01R 33/5608G06T 7/30G01R 33/5616G06T 3/0093G06T 3/18
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Claims

Abstract

A method for mapping brain function of a subject includes generating a lesion mask using a search light algorithm based on a plurality of anatomical images of the subject. The plurality of anatomical images are registered with atlas images by nonlinear atlas registration using the generated lesion mask to generate a warping map. A plurality of functional images of the subject are resampled using the warping map to generate a functional map, functional connectivity is computed using the functional map and a multi-layer perceptron.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method for mapping brain function of a subject, the method comprising:
 generating a lesion mask using a search light algorithm based on a plurality of anatomical images of the subject;   registering the plurality of anatomical images with atlas images by nonlinear atlas registration using the generated lesion mask to generate a warping map;   resampling a plurality of functional images of the subject using the warping map to generate a functional map; and   computing functional connectivity using the functional map and a multi-layer perceptron.

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