US2023013015A1PendingUtilityA1

Composition for the treatment of urinary tract infections

Assignee: MANN KEVEHAZI LAURAPriority: Dec 24, 2019Filed: Sep 23, 2022Published: Jan 19, 2023
Est. expiryDec 24, 2039(~13.4 yrs left)· nominal 20-yr term from priority
A61K 36/82A61K 36/324A61K 31/7004A61K 36/9066A61K 36/67A61P 13/02A61P 13/06A61P 31/04A61K 36/42Y02A50/30
53
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Claims

Abstract

A composition for the treatment of UTIs comprising: One of, a monosaccharide L-arabinose, L-frucose, D-mannose, L-rhamnose, L-xylose, lyxose or galactose; Extract from one of Boswellia serrata, Boswellia sacra or Boswellia carteri containing boswellic acids, terpenes and incensole acetate; Extract from the seeds of one of, Cucurbitaceae maxima, Cucurbitaceae pepo or Cucurbitaceae moschata; Turmeric extract; Green tea extract containing polyphenolic catechins; and, Piper nigrum.

Claims

exact text as granted — not AI-modified
1 . A composition comprising:
 D-mannose;   Extract from one of Boswellia serrata, Boswellia sacra or Boswellia carteri containing boswellic acids, terpenes and incensole acetate;   Pumpkin seed extract;   Turmeric extract;   Green tea extract containing polyphenolic catechins; and   Piper nigrum.   
     
     
         2 . A composition according to  claim 1  comprising:
 D-mannose from 400 mg-500 mg per single dose; 
 Extract from one of Boswellia serrata, Boswellia sacra or Boswellia carteri containing boswellic acids, terpenes and incensole acetate from 100-200 mg per single dose; 
 Pumpkin seed extract from 100-200 mg per single dose; 
 Turmeric extract from 100 mg per single dose; 
 Green tea extract containing polyphenolic catechins from 30 mg per single dose; and, 
 Piper nigrum from 5 mg per single dose. 
 
     
     
         3 . A composition according to  claim 1  in the form of a powder comprising:
 D-mannose in an amount from 400-500 mg per single dose; 
 From 100-200 mg per single dose Boswellia extract having at least 65% boswellic acid; 
 Water soluble pumpkin seed extract from 100-200 mg per single dose; 
 From 100-200 mg per single dose Turmeric extract containing 65-95% curcuminoids; 
 Green tea EGCG extract, from 30-50 mg per single dose; and, 
 Piper nigrum from 5-10 mg per single dose. 
 
     
     
         4 . A composition according to  claim 1  in the form of a liquid or gel comprising:
 D-mannose in an amount from 400-500 mg per single dose; 
 From 100-200 mg per single dose Boswellia extract having at least 65% boswellic acid; 
 Pumpkin seed oil extract from 100-200 mg per single dose; 
 From 100-200 mg per single dose Turmeric extract containing 65-95% curcuminoids; 
 Green tea EGCG extract, from 30-50 mg per single dose; and, 
 Piper nigrum from 5-10 mg per single dose. 
 
     
     
         5 . A composition according to  claim 1  in the form of a liquid or gel comprising:
 D-mannose in an amount from 1500-1700 mg per single dose; 
 From 300-500 mg per single dose Boswellia extract having at least 65% boswellic acid; 
 Pumpkin seed oil extract, from 500-700 mg per single dose; 
 From 500-700 mg per single dose Turmeric extract containing 65-95% curcuminoids; 
 Green tea EGCG extract, from 90-150 mg per single dose; and, 
 Piper nigrum from 5-20 mg per single dose. 
 
     
     
         6 . A composition according to  claim 1  in the form of a power in a capsule comprising:
 D-mannose 400 mg; 
 Pumpkin seed extract equivalent to 150 mg; 
 Turmeric extract equivalent to 150 mg; 
 Boswellia Serrata extract equivalent to 100 mg; 
 Green Tea Extract 95% Polyphenols 30 mg 
 Black pepper 5 mg; and optionally a pharmaceutically acceptable carrier, excipient or diluent. 
 
     
     
         7 . The composition according  claim 1 , wherein the pumpkin seed extract is from the seeds of one of Cucurbitaceae maxima, Cucurbitaceae pepo or Cucurbitaceae moschata. 
     
     
         8 . A composition according to  claim 1 , for use in combating and reliving the symptoms of a urinary tract infection. 
     
     
         9 . A composition according to  claim 1 , for use in combating the recurrence of a urinary tract infection. 
     
     
         10 . A composition according to  claim 1 , for use as an antispasmodic for those suffering with overactive bladder syndrome. 
     
     
         11 . A composition according to  claim 1 , for use in combating post coital/sexual activity triggered UTIs. 
     
     
         12 . A composition for use in the treatment of a urinary tract infection by administering four capsules three times a day for a minimum of 5 days, wherein the capsule comprises:
 D-mannose 400 mg,   Pumpkin seed extract 10:1 (equivalent to 150 mg),   Turmeric extract 10:1 (equivalent to 150 mg),   Boswellia Serrata extract 5:1 (equivalent to 100 mg),   Green Tea Extract 95% Polyphenols 30 mg,   Black pepper 5 mg; and optionally a pharmaceutically acceptable carrier, excipient or diluent.   
     
     
         13 . A composition according to  claim 2 , in the form of a powder comprising:
 D-mannose in an amount from 400-500 mg per single dose;   From 100-200 mg per single dose Boswellia extract having at least 65% boswellic acid;   Water soluble pumpkin seed extract from 100-200 mg per single dose;   From 100-200 mg per single dose Turmeric extract containing 65-95% curcuminoids;   Green tea EGCG extract, from 30-50 mg per single dose; and,   Piper nigrum from 5-10 mg per single dose.   
     
     
         14 . A composition according to  claim 2 , in the form of a liquid or gel comprising:
 D-mannose in an amount from 400-500 mg per single dose;   From 100-200 mg per single dose Boswellia extract having at least 65% boswellic acid;   Pumpkin seed oil extract from 100-200 mg per single dose;   From 100-200 mg per single dose Turmeric extract containing 65-95% curcuminoids;   Green tea EGCG extract, from 30-50 mg per single dose; and,   Piper nigrum from 5-10 mg per single dose.   
     
     
         15 . A composition according to  claim 1  for daily use in women at Menopause, for prevention of urinary tract infections, comprising:
 D-mannose from 1600-2000 mg (or 1600-1700 mg) per daily dose; 
 Pumpkin seed extract from 400-800 mg per daily dose; 
 Turmeric extract from 400-800 mg per daily dose; 
 Boswellia Serrata extract from 400-800 mg per daily dose; 
 Green Tea extract 65-95% polyphenols from 90-120 mg per daily dose, and 
 Black pepper 20 mg per daily dose. 
 
     
     
         16 . A composition according to  claim 1 , wherein the composition is a powder contained in a capsule. 
     
     
         17 . A composition according to  claim 1 , wherein the composition is a powder contained in a sachet. 
     
     
         18 . A composition according to  claim 1 , wherein the composition is a liquid. 
     
     
         19 . A composition according to  claim 1 , wherein the composition is a gel.

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