Trpv1 activation-modulating complex mixtures of cannabinoids and/or terpenes

Abstract

Described are methods of modulating the activation of the TRPV1 ion channel by administering at least one cannabinoid and/or terpene compound.

1 - 57 . (canceled) 
     
     
         58 . A method of treating a subject, comprising:
 administering to a subject who has asthma, an effective amount of a pharmaceutical composition comprising cannabigerolic acid (CBGA), wherein after administration, CBGA contacts a TRPV1-expressing cell.   
     
     
         59 . The method of  claim 58 , wherein the pharmaceutical composition further comprises cannabinol (CBN), cannabidiol (CBD), cannabigerol (CBG), or cannabidivarin (CBDV). 
     
     
         60 . The method of  claim 58 , wherein the pharmaceutical composition further comprises at least one terpene, wherein the at least one terpene is selected from myrcene, beta-caryophyllene, limonene, linalool, phytol, nerolidol, and pinene. 
     
     
         61 . The method of  claim 60 , wherein the at least one terpene is myrcene. 
     
     
         62 . The method of  claim 59 , wherein the pharmaceutical composition comprises cannabigerol (CBG). 
     
     
         63 . The method of  claim 60 , wherein the pharmaceutical composition further comprises myrcene and beta-caryophyllene. 
     
     
         64 . The method of  claim 58 , wherein contacting the cell kills the contacted cell. 
     
     
         65 . The method of  claim 58 , wherein contacting the cell does not kill the contacted cell.